期刊文献+

妊娠期妇女血中α1-抗胰蛋白酶与纤维蛋白原相关性研究 被引量:11

Correlation ofα1-Antitrypsin and Fibrinogen in Pregnancy
暂未订购
导出
摘要 目的 了解正常非孕妇女及早、中、晚各妊娠期妇女血中 αl-AT及FIB的浓度,分析这2种因子的变化及相互关系。方法 采用免疫比浊法检测74例非孕及早、中、晚妊娠妇女血浆中的 αl-AT及FIB的浓度。结果 αl-AT随孕周增加而减少,FIB随孕周增加而增加,FIB与 α1-AT呈显著负相关,两者的回归方程为 y=-79.12x+619.18(x为 α1-AT,y为FIB)。结论al-AT参与妊娠期凝血抗凝系统的调节,αl-AT对妊娠期间高凝状态有重要作用。 Objective To evaluate the normal concentrations of αl-AT and FIB in both non-pregnancies and pregnancies at early stage, middle stage and late stage and analyze the correlation between the two factors. Methods Immunoturbidimetric assay methods were used to detect αl-AT and FIB in 74 samples. Results α l-AT was decreased and FIB was increased with the pregnancy stage. FIB and α l-AT had significantly negative correlation. The linear equation was y=-79.12x+619.18 (x is α l-AT, y is FIB). Conclusion The α l-AT takes part in the regulation of the coagulation and fibrolysis system in pregnancies; α l-AT is an important factor in high coagulation condition in pregnancies.
出处 《中国实验诊断学》 2000年第4期160-161,共2页 Chinese Journal of Laboratory Diagnosis
关键词 Α1-抗胰蛋白酶 纤维蛋白原 妊娠 αl-Antitrypsin Fibrinogen Pregnancy
  • 相关文献

参考文献6

  • 1TravisJ,SalvesenG.Controlofcoagulationandfibrinolysisbyplasmaproteinaseinhibitors[J].BehringInstMitt,1983,73:56.
  • 2DatiF,PelzerH,WagnerC.Relevanceofmarkersofhemostasisactivationinobstertics/gynecologyandpediatrics[J].SeminThrombHemost,1998,24(5):443.
  • 3EspanaF,GilabertJ,VicenteV,etal.ActivatedproetinC:alphy1-antitrypsin(APC:alpha1AT)complexasamarkerforinvitrodiagnosisofprethromboticstates[J].ThrombRes,1992,66(55):499.
  • 4WuilleminWA,HackCE,BleekerWK,etal.InactivationfactorXIainvivo:Studiesinchimpanzeesandinhumans[J].ThrombHeamost,1996,76(4):549.
  • 5MarioCastellucci,ThomasTheelen,ElenaPompoli,etal.Immuohistochemicallocalizationofserine-proteaseinhibitorsinthehumanplaceenta[J].CellTissueRes,1994,(278):283.
  • 6张志诚.临床产科学[M](第1版)[M].天津:天津科学技术出版社,1994.222-4.

共引文献2

同被引文献29

  • 1林丽华,黄立文,林秀凤.正常临产妇血清脂类水平分析[J].海峡预防医学杂志,2001,7(4). 被引量:1
  • 2陈静,林寿榕.90例待产妇血清蛋白电泳图谱分析[J].国外医学(临床生物化学与检验学分册),2005,26(9):579-580. 被引量:6
  • 3郭小芳,卢光进,李庆富,周炜茹.临产妇与其新生儿血清锌铜含量测定及相关分析[J].微量元素与健康研究,1996,13(3):22-24. 被引量:2
  • 4金梅枝,付雪芹.血清蛋白电泳的临床应用[J].中国医药指南,2007,5(5):111-112. 被引量:3
  • 5杨进.足月妊娠妇女血浆凝血因子活性的观察[J].第一军医大学学报,1993,13(3):288-288.
  • 6[5]Peerschke EIB. Recognition of platelet-associated fibrinogen by ploy-clonal antibodies: correlation with platelet aggregation. Blood, 1992,79: 20 ~ 28.
  • 7[4]乐杰主编.妇产科[M].北京:人民卫生出版社,2002:22.
  • 8周新,涂植光.临床生物化学和生物化学检验[M].3版.北京:人民卫生出版社,2004:57.
  • 9郭小芳 卢先进 李庆富 等.临产妇新生儿血清锌铜含测定及相关性分析.微量元素与健康研究,2002,13(6):22-24.
  • 10原韪 曹树军 刘菊玲.妊娠中晚期血清蛋白的变化.郧阳医学院学报,1999,9:15-15.

引证文献11

二级引证文献40

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部