摘要
目的 :研究肝硬化患者血浆中 D—二聚体和抗凝血酶— ( AT— )的改变及其临床意义。方法 :D—二聚体采用 EL ISA法 ,AT— 采用免疫散射比浊法。结果 :肝硬化失代偿期病人 D—二聚体水平明显高于对照组 ,P<0 .0 1,并随肝功能减退而升高 ,而 AT— 水平明显低于对照组 ,P<0 .0 1,并随肝功能减退而降低。结论 :肝硬化病人抗凝和纤溶指标均有异常改变 ,并有助于肝功能损害程度及预后的判断。
Objectives:[WT5BZ]To investigate the change and clinical significance of D-dimer and antithrombin-Ⅲ (AT-Ⅲ) in the plasma of patients with decompensation of liver cirrhosis [WT5HZ]Method: [WT5BZ]The plasma levers of D-dimer and AT-Ⅲ in patients with liver cirrhosis (Group I,n=38) were compared to that in healthy people (Group Ⅱ as control,n=25).[WT5HZ]Results:[WT5BZ]The plasma level of D-dimer in Group I was higher (P<0.01),which increased as liver function getting worse.But the level of AT-Ⅲ in Group I was lower (p<0.01),and it came down accompanying with liver function failing.[WT5HZ]Conclusions:[WT5BZ]It indiacated that anticoagulant system and fibrinolysis system had changed in decompensation of liver cirrhosis and showed the degree of liver function disorder and prognosis. [WT5HZ]
出处
《河北医学》
CAS
2000年第9期811-813,共3页
Hebei Medicine
