摘要
目的:探讨临床药师在异基因外周血干细胞移植(allo-PBSCT)患者临床治疗中发挥的作用。方法:通过临床药师对2例allo-PBSCT患者实施药学监护,参与制订治疗方案,全程参与临床查房、病例讨论,对患者进行药学监护和用药教育。结果:A患者allo-PBSCT术后第11天,血常规提示造血重建;期间监测巨细胞病毒(HCMV-DNA)结果呈阴性;骨髓细胞学示骨髓增生明显活跃;患者生命征平稳,无发热等不适反应。B患者allo-PBSCT术后第11天,血常规提示造血重建。期间监测HCMV-DNA结果呈阴性;骨髓细胞学示粒系增生,红系增生低下;患者无发热、皮疹等移植物抗宿主病(GVHD)表现。结论:临床药师通过参与allo-PBSCT患者的药学监护,协同医师制订用药方案,可提高医师、护士和患者对临床药师的认可,减少药品不良反应,提高药物治疗效果,体现临床药师的价值。
OBJECTIVE： To study the role of clinical pharmacists in the treatment for patients with allogeneic peripheral blood stem cell transplantation （allo-PBSCT）. METHODS： Clinical pharmacists provided pharmaceutical care for 2 cases of allo-PBSCT, participated in the formulation of therapeutic plan, ward-round and case discussion, and carried out pharmaceutical care and medica- tion education. RESULTS： 11 days after allo-PBSCT, routine blood test of patient A reminded hematopoietic reconstruction; HC- MV-DNA was negative; bone marrow inspection showed active bone marrow hyperplasia; the vital signs of patients were stable without fever and other ADR. 11 days after allo-PBSCT, routine blood test of patient B reminded hematopoietic reconstruction; HC- MV-DNA was negative; bone marrow inspection showed myeloid cell hyperplasia and low erythroid cell hyperplasia; no fever, ery- thra and other GVHD manifestation were found. CONCLUSION： Through clinical pharmacists participate in pharmaceutical care for alIo-PBSCT patients, and collaborate with doctors on medical plan to improve the acceptance of doctors, nurses and patients for clinical pharmacists and realize the value of them.
出处
《中国药房》
CAS
CSCD
2012年第42期4019-4021,共3页
China Pharmacy
关键词
临床药师
异基因外周血干细胞移植
药学监护
Clinical pharmacist
Allogeneic peripheral blood stem cell transplantation
Pharmaceutical care
