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我院160例酪氨酸激酶抑制剂致不良反应分析

Analysis of 160 Cases of Adverse Drug Reaction of Tyrosine Kinase Inhibitor in Our Hospital
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摘要 目的:观察酪氨酸激酶抑制剂治疗癌症的不良反应。方法:定期随访服用酪氨酸激酶抑制剂的160例患者,对其服药后的情况进行分析、总结。结果:酪氨酸酶抑制剂引起的不良反应以皮肤系统损害最为常见(占43.88%),其次是消化系统和呼吸系统。结论:临床上要对使用酪氨酸酶抑制剂的患者加强监测,以免严重不良反应的发生。 OBJECTIVE: To observe adverse drug reactions (ADR) of tyrosine kinase inhibitors in the treatment of cancer. METHODS: 160 patients who took tyrosine kinase inhibitors were followed up regularly, and their conditions were summarized and analyzed after medication. RESULTS: The most common ADR caused by tyrosine kinase inhibitor was lesion of skin damage (43.88%), followed by digestive system and respiratory system. CONCLUSION: We should strengthen monitoring for patients who use tyrosine kinase inhibitors, so as to avoid the occurrence of serious ADR.
出处 《中国药房》 CAS CSCD 2012年第42期3997-3999,共3页 China Pharmacy
关键词 表皮生长因子受体 酪氨酸激酶抑制剂 药品不良反应 Epidermal growth factor receptor Tyrosine kinase inhibitor Adverse drug reaction
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