摘要
目的:观察国产培美曲塞治疗晚期非小细胞肺癌的疗效及不良反应。方法:回顾性分析我院收治的62例晚期非小细胞肺癌患者,按照使用培美曲塞种类的不同分为2组,A组使用国产培美曲塞,B组使用进口培美曲塞,比较2组用药1年后的疗效及不良反应。结果:2组用药1年后的疗效及不良反应差异均无统计学意义(P>0.05)。结论:国产培美曲塞用于晚期非小细胞肺癌治疗1年后的疗效及不良反应与进口培美曲塞相近。
OBJECTIVE： To observe clinical efficacy and adverse drug reactions of domestic pemetrexed in the treatment of non-small cell lung cancer （NSCLC）. METHODS： 62 patients with advanced NSCLC admitted in our hospital were analyzed retro- spectively, and they were divided into 2 groups according to different kinds of pemetrexed. Group A was given domestic peme- trexed, group B was given imported pemetrexed. Therapeutic efficacy and adverse drug reactions were compared between 2 groups after 1 year of treatment. RESULTS： After 1 year, therapeutic efficacy and adverse drug reactions of 2 groups had no significant differences （P〉0.05）. CONCLUSION： Clinical efficacy and adverse drug reactions of domestic pemetrexed are similar to imported pemetrexed for NSCLC 1 year later.
出处
《中国药房》
CAS
CSCD
2012年第42期3992-3994,共3页
China Pharmacy
关键词
培美曲塞
非小细胞肺癌
疗效
不良反应
Pemetrexed
Non-small.cell lung cancer
Clinical efficacy
Adverse drug reactions
