摘要
目的:采用多指标综合评分法对清热解毒口服液的处方提取工艺进行筛选。方法:以黄芩苷和栀子苷提取率综合方差贡献率为指标,选择提取时间和加水量为考察因素,采用中心复合设计法优选提取工艺,并对因素参数进行预测分析。结果:最优提取工艺为:提取时间139 min,加水量13倍,综合评分指标为0.768。结论:多指标综合评分法非常适合多成分提取的实验设计,其具有应用简便、预测性好等优点。
Objective：To optimize the extraction process for Qingrejiedu oral liquid with synthesizing multiple guidelines grading method.Methods：Used the extraction rate of baicalin and geniposide comprehensive contribution rate variance as index,extraction time and added water were as factors,central composite design was used for optimization of extraction process,and forecasting analysis parameters.Results：The optimal extraction process was as follows： extraction time 139 min,added water 13 times,grading index was 0.768.Conclusion： Synthesizing multiple guidelines grading method is ideal for multi-component extraction experiment design,its easy application,the forecast is good and so on.
出处
《中药材》
CAS
CSCD
北大核心
2012年第8期1326-1330,共5页
Journal of Chinese Medicinal Materials
关键词
多指标综合评分法
清热解毒口服液
提取工艺
Synthesizing multiple guidelines grading method
Qingrejiedu oral liquid
Extraction process
