摘要
目的通过对不同病期的血清中β2-微球蛋白、视黄醇结合蛋白和胱抑素-C的联合检测，评价其对急性肾损伤早期诊断的临床价值。方法选择住院急性肾损伤（AKI）患者88例和同期健康体检者63例，在日立7600-020全自动生化分析仪同时检测血清中β2-微球蛋白、视黄醇结合蛋白和胱抑素-C的含量。结果急性肾损伤各期患者血清中β2-微球蛋白、胱抑素C和视黄醇结合蛋白较对照组明显升高（P〈0．05或P〈0．01）。结论血清中β2-微球蛋白、胱抑素C和视黄醇结合蛋白均是急性肾损伤早期诊断的敏感指标，三项联合检测有助于早期诊断急性肾损伤。
Objective Through different disease period the serum β2-microglobulin（ β2-MG）, Retinal bind- ing protein（RBP） and Cystatin C（Cys-C） joint test,to evaluate the clinical value of the combination detection of ear- ly diagnosis of acute kidney injury（AKI）. Methods Our choice in March 2011 to February 2012 in the same period and 88 patients with AKI physical examination in 63 cases,in the new HITACHI7600-020 automatic biochemistry ana- lyzer and into test sample β2-MG, RBP and Cys-C content. Results The patients with AKI of serum β2-MG, RBP and Cys-C compared with the control were significantly increased, the differences were significant （ P 〈 0.05 or P 〈 0. 01 ）. Conclusion Serum β2-MG, RBP and Cys-C are sensitive idicators in early diagnosis of AKI, three united de- tection help early diagnosis AKI, clinical doctors can provide reliable accurate valuable diagnostic basis for guidance.
出处
《中国基层医药》
CAS
2012年第20期3072-3073,共2页
Chinese Journal of Primary Medicine and Pharmacy
关键词
Β2-微球蛋白
视黄醇结合蛋白
胱抑素C
肾损伤
β2-microglobulin
Retinal binding protein
Cystatin C
Acute kidney injury （AKI）
