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儿童闭塞性细支气管炎的诊断与治疗建议 被引量：137

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摘要 闭塞性细支气管炎（bronchiolitis obliterans，BO）是一种细支气管炎性损伤所致的慢性气流受限综合征。目前无确切的发病率统计，感染后BO（post—infectious bronchiolitis obliterans，PBO）的报道多见于南美洲及亚洲国家（如巴西、智利、阿根廷、乌拉圭、韩国等），有文献称大约有1％的急性病毒性细支气管炎可能发展成BO。BO病理上表现为细支气管的部分或完全闭塞，临床表现为重症肺炎或其他原因引起的气道损伤后持续咳嗽、喘息、呼吸困难，影响儿童的身体健康和生活质量。
作者 无 申昆玲(整理) 王维(整理)
机构地区 中华医学会儿科学分会呼吸学组 《中华儿科杂志》编辑委员会 首都医科大学附属北京儿童医院呼吸科 不详
出处 《中华儿科杂志》 CAS CSCD 北大核心 2012年第10期743-745,共3页 Chinese Journal of Pediatrics
关键词 闭塞性细支气管炎 儿童 病毒性细支气管炎 治疗 诊断 气流受限 炎性损伤 亚洲国家
分类号 R725.6 [医药卫生—儿科]
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参考文献19

  • 1Smith K J, Fan LL. Insights into post-iirfectious bronchiolitisobliterans in children . Thorax ,2006,6l :462-463.
  • 2Zhang L, Silva FA. Bronchiolitis obliterans in children. J Pediatr ( Rio J) ,2000,76 : 185-192.
  • 3Nicod LP. Mechanisms of airway obliteration after lung transplantation. Proc Am Thorac Soc ,2006,3:444-449.
  • 4A Kurland G, Michelson P. Bronchiolitis obliterans in children. Pediatr Pulmonol, 2005,39 : 193-208.
  • 5Kamada N, Kinoshita K, Togawa Y, et al. Chronic pulmonary complications associated with toxic epidermal necrolysis: Report of a severe case with anti-Ro/SS-A and a review of the published.
  • 6DudekAZ, Mahaseth H, DeFor TE, et al. Bronchiolitis obliterans in chronic graft-versus-host disease: analysis of risk factors and treatment outcomes. Biol Blood Marrow Transplant, 2003, 9:657- 666.
  • 7Fischer GB, Sarria EE, Mattiello R, et al. Post infectious bronchiolitis obliterans in children. Paediatr Respir Rev, 2010, 11:233-239.
  • 8王维,申昆玲,曾津津.儿童闭塞性细支气管炎42例临床分析[J].中华儿科杂志,2008,46(10):732-738. 被引量：60
  • 9Siegel MJ, Bhalla S, Gutierrez FR, et al. Post-lung transplantation bronchiolitis obliterans syndrome: usefulness of expiratory thin-section CT for diagnosis. Radiology, 2001,220: 455-462.
  • 10Colom A J, Teper AM. Clinical prediction rule to diagnose post- infectious bronchiolitis obliterans in children. Pediatr Pulmonol, 2009,44 : 1065-1069.

二级参考文献26

  • 1Ratjen F, Rjabko O, Kremens B. High-dose eorticosteroid therapy for bronchiolitis obliterans after bone marrow transplantation in children. Bone Marrow Transplant ,2005,36 : 135-138.
  • 2Zhang L, Silva FA. Bronchiolitis obliterans in children. J Pediatr (Rio J) ,2000,76:185-192.
  • 3Colom AJ, Teper AM, Vollmer WM, et al. Risk factors for the development of bronchiolitis obliterans in children with bronchiolitis. Thorax, 2006,61:503-506.
  • 4Teper A, Fischer GB, Jones MH. Respiratory sequelae of viral diseases : from diagnosis to treatment. J Pediatr ( Rio J), 2002, 78 : 187-194.
  • 5Yalcin E, Dogru D, Haliloglu M, et al. Postinfectious bronchiolitis obliterans in children: clinical and radiological profile and prognostic factors. Respiration, 2003,70:371-375.
  • 6Kim CK, Kim SW, Kim JS, et al. Bronchiolitis obliterans in the 1990s in Korea and the United States. Chest, 2001,120: 1101- 1106.
  • 7Hogg JC. Childhood viral infection and the pathogenesis of asthma and chronic obstructive lung disease. Am J Respir Crit Care Med, 1999, 160:26-28.
  • 8Kurland G, Michelson P. Bronchiolitis obliterans in children. Pediatr Pulmonol, 2005,39 : 193-208.
  • 9Kamada N, Kinoshita K, Togawa Y, et al. Chronic pulmonary complications associated with toxic epidermal necrolysis: report of a severe case with anti-Ro/SS-A and a review of the published work. J Dermatol,2006, 33:616-622.
  • 10Smith K J, Fan LL. Insights into post-infectious bronchiolitis obliterans in children. Thorax ,2006,61:462-463.

共引文献81

同被引文献955

引证文献137

二级引证文献894

中华儿科杂志
2012年 第10期

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