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神经电生理监测技术在椎管内病变术中的应用 被引量:25

Application of intraoperative neurophysiological monitoring in spinal cord surgery
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摘要 目的:探讨术中神经监测(intraoperative neurophysiological monitoring,IONM)在脊髓手术中的应用。方法:对24例脊髓手术患者,根据监测方法不同分为4组。A组(腹侧肿瘤)行体感诱发电位(somatosensory evokedpotential,SEP)、运动诱发电位(motor evoked potential,MEP)及肌电图(electromyography,EMG)监测;B组(髓内肿瘤)行SEP+MEP监测;C组(髓外硬膜下肿瘤)行SEP+EMG监测;D组(马尾神经病变)行EMG监测,分析术中监测情况与术后神经功能变化之间的关系。结果:A组3例,术中均有监测报警,手术结束前均恢复,但有1例出现术后神经功能恶化。B组6例,术中均有监测报警,手术结束前5例恢复,1例未恢复者术后神经功能恶化。C组9例,其中7例术中监测报警,手术结束前均恢复,但有1例出现术后神经功能恶化。D组6例,术中均有监测报警,手术结束前均恢复,但有1例出现术后神经功能恶化。结论:IONM可及时提醒术者患者的神经系统可能存在功能损伤,从而采取补救措施,有助于减少术后神经功能恶化,但部分患者采取措施后监测虽恢复,仍出现不同程度的神经功能恶化,IONM还需要进一步完善。 Objective:To study application of intraoperative neurophysiological monitoring(IONM) in spinal cord surgery.Methods: In the study,24 patients with spinal cord tumors were divided into 4 groups according to the method of monitoring.Group A(ventral tumors) underwent somatosensory evoked potential(SEP) + motor evoked potential(MEP) + electromyography(EMG) monitoring,group B(intramedullary tumors) underwent SEP + MEP monitoring,group C(subdural extramedullary tumors) underwent SEP + EMG monitoring,group D(conus medullary and cauda equina lesions) underwent EMG monitoring.The relationship between changes of IONM and postoperative neurological function was analyzed.Results: All of the 3 patients in group A had IONM alteration which recovered before the end of surgery,but neurological function deteriorated in 1 case.All of the 6 patients in group B had IONM alteration,of whom 5 recovered before the end of surgery,and 1 did not recover and neurological function deteriorated in this case.Seven of the nine patients in group C had IONM alteration which recovered before the end of surgery,but neurological function deteriorated in 1 case.All of the 6 patients in group D had IONM alteration which recovered before the end of surgery,but neurological function deteriorated in 1 case.Conclusion: IONM is useful to reduce postoperative neurological deterioration.However,IONM neurophysiological monitoring needs further improvement.
出处 《北京大学学报(医学版)》 CAS CSCD 北大核心 2012年第5期776-779,共4页 Journal of Peking University:Health Sciences
关键词 电生理学 脊髓 监测 手术中 脊神经根 Electrophysiology Spinal cord Monitoring intraoperative Spinal nerve roots
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参考文献8

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