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单唾液酸四己糖神经节苷酯联合多奈哌齐治疗老年血管性痴呆疗效 被引量:10

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摘要 目的观察单唾液酸四己糖神经节苷酯(MSTHG)联合多奈哌齐治疗老年血管性痴呆(VD)疗效。方法 70例老年VD患者随机均分为2组:A组为多奈哌齐+MSTHG联合治疗组;B组单用多奈哌齐治疗。分别在治疗前和治疗6个月后进行MoCA评分、MSSE评分、ADL评分,判定疗效。结果治疗后,A组有效率为94.3%,明显高于B组的80.0%(P<0.05)。治疗后,两组MoCA评分、MMSE评分较治疗前均明显增加(P<0.05),A组高于B组(P<0.05);治疗后,两组ADL评分均明显减低(P<0.05),A组低于B组(P<0.05)。结论多奈哌齐+MSTHG联合治疗比单用多奈哌齐治疗更能进一步改善老年VD患者的认知功能、日常生活能力及社会活动功能。
出处 《江苏医药》 CAS CSCD 北大核心 2012年第19期2324-2325,共2页 Jiangsu Medical Journal
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