摘要
目的:探讨进一步优化重型颅脑损伤病人的综合营养支持治疗措施。方法:52例重型颅脑损伤病人按采用不同的营养支持治疗措施分为常规组(n=24)和改进组(n=28)。改进组在传统营养支持治疗措施的基础上再给予早期肠道喂养(EEF)、谷氨酰胺(Gln)和重组人生长激素(rhGH)等综合营养支持治疗。观察两组病人感染的发生率、第30天病死率和转出ICU时间。并于入院即刻、入院后第1、7、14和21天定时检测病人血清清蛋白(ALB)、前清蛋白(PA)水平。在入院72 h后应用rhGH,测量两组病人入院第3、7、14和21天的空腹血糖。结果:①改进组病人转出ICU时间短于常规组(P<0.05)。②改进组病人感染并发症的发生率明显下降(P<0.05)。③两组病人ALB水平均明显下降,但常规组下降更为明显(P<0.05)。结论:EEF联合Gln和rhGH治疗有助于改善重型颅脑损伤病人的营养状况,提高免疫功能,降低感染发生率,缩短ICU的入住时间。
Objective： To investigate nutritional support in severe craniocerebral injury.Methods： 52 cases were divided by different periods into two groups ： group N（n =24）and group A（n = 28）.Group A was treated with early enteral feeding（EEF）,recombinant human growth hormone（rhGH）and glutamine（Gln）.Plasma albumin and pre-albumin levels were measured immediately after hospitalization and day 1,7,14,21 after treatment.Results： ①The days in ICU in group A was shorter than in group N（P0.05）.②The incidence in stress ulcer and lung infection in group A was significantly lower than in group N（P0.05）.③Plasma albumin and pre-albumin levels were decreased in two groups and was more serious in the group N（P0.05）.Conclusion： The combination use of early enteral feeding（EEF）,recombinant human growth hormone（rhGH）,and glutamine（Gln）can improve the nutrition station of severe craniocerebral injury.
出处
《肠外与肠内营养》
CAS
北大核心
2012年第5期267-269,共3页
Parenteral & Enteral Nutrition
关键词
重型颅脑损伤
肠内营养
重组人生长激素
谷氨酰胺
Severe craniocerebral injury
Enteral nutrition
Recombinant human Growth hormone
Glutamine
