摘要
目的:分析BPH患者下尿路感染的细菌谱和耐药性,为医生应用敏感抗生素提供参考。方法:回顾性分析了2005年6月～2011年1月我院370例BPH患者尿培养结果。结果:尿培养阳性者共144例(38.9%),平均年龄50～87(70.94±8.80)岁。前五位细菌:大肠埃希氏杆菌(25.0%)、粪肠球菌(15.3%)、溶血葡萄球菌(9.7%)、铜绿假单胞菌(9.0%)和肺炎克雷伯菌(6.9%)。大肠埃希氏菌,对所有抗生素的耐药性都大于20%。75%以上细菌为复合耐药菌。其中青霉素的耐药性是最高,依次是头孢类抗生素、喹诺酮类和磺胺类药物。结论:BPH患者下尿路感染的细菌中,大肠杆菌是最主要的细菌,75%以上细菌为复合耐药菌。对于复合耐药菌治疗中,青霉素和头孢类抗生素应该慎用。应长期动态观察BPH患者下尿路细菌谱和耐药性的变化。
Objective： To analyze micro-organisms demography and resistance characteristics in the BPH patients of lower UTI and provide for doctors with sensitive antibiotics. Method：From June 2005 to January 2011 ,all of 370 urine samples of BPH were sent to be cultivated. Result：One hundred and forty-four（38.9 % ）were positive. The mean age of patients was （70.94±8.80） years old. The five valuable microorganisms： Escherichia coli （25.0% ）, E. faecalis （ 15.3 % ）, Staphylococcus （ 9.7%） Pseudomonas aeruginosa （ 9.0 % ） and Klebsiella pneumoniae （6.9%）. The resistance of Escherichia coli to all antimicrobial was 〉20%. Over 75% of all positive micro-organism Were multiple-resistant. Of all medicine-resistant bacteria, penicillin was the highest resistance, the next three were Cephalosporins,Quinolones and trimethoprim-sulfamethoxazole respectively. Conclusion： Escherichia coli is a major microorganism in BPH of patients with UTI. Positive bacteria 〉75 % are all multiple-resistance. We should pay more attention to the use of penicillin and Cephalosporins in the therapy of multiple-resistance microorganisms. Therefore,it is necessary that long-term and dynamic observations should be done to change of the micro-organisms demography in BPH patients.
出处
《临床泌尿外科杂志》
2012年第10期767-769,773,共4页
Journal of Clinical Urology
