摘要
目的 评价术前MRI检查与难治性颞叶癫痫经过手术切除治疗后短期内预后关系。方法 中国医科大学附属盛京医院神经外科自2009年1月至2010年12月共收治通过临床发作症状学以及视频脑电图诊断为颞叶癫痫的患者34例，按照MRI检查有无病灶分为2组，其中有病灶组18例，未发现病灶组16例。手术治疗后半年及1年，按照国际抗癫痫联盟（ILAE）术后疗效评估分类法判断2组患者不同预后情况。结果 34例患者中术后半年达到ILAE-1级的有23例，占67．6％；术后1年达到ILAE-1级的有20例，占58．8％。其中有病灶组患者术后半年达到ILAE-1级的有16例，占88．9％；术后1年有14例，占77．8％；未发现病灶组患者术后半年达到ILAE-1级的有7例，占43．75％；术后1年有6例，占37．5％；差异均有统计学意义（P〈0．05）。结论 外科手术治疗对于颞叶难治性癫痫是一种有效的治疗方式；MRI检查阳性的颞叶癫痫患者宜积极行手术治疗。
Objective To assess the relationship between preoperative MRI and short-term outcome of refractory temporal epilepsy treated by temporal lobectomy. Methods Thirty-four patients with temporal lobe epilepsy, admitted to our hospital from January 2009 to December 2010 and diagnosed by ictal semeiology and video EEG, were divided into two groups according to the lesions detected by MRI （1 8 with lesions and 16 without lesions）. The postoperative outcomes 6 months and one year after the surgery were evaluated according to International League Against Epilepsy （ILAE） classification. Results In all the 34 patients, 23 patients （67.6%） were seizure-free （ILAE- grade 1） 6 months after surgery and 20 （58.8%） were seizure-free one year after surgery. In 18 patients with lesions, 16 patients （88.9%） were seizure-free 6 months after surgery, and 14 （77.8%） one year after surgery; in 16 patients without lesions, 7 patients （43.75%） were seizure-free 6 months after surgery, and 6 （37.5%） one year after surgery; statistical difference was noted between the 2 groups （P〈0.05）. Conclusion Epilepsy surgery is an effective treatment option for refractory temporal lobe epilepsy; the patients with lesions correlated to clinical seizure should be treated by surgery.
出处
《中华神经医学杂志》
CAS
CSCD
北大核心
2012年第10期977-981,共5页
Chinese Journal of Neuromedicine
关键词
颞叶癫痫
视频脑电图
颞叶切除
Temporal lobe epilepsy
Video- Electroencephalogram
Temporal lobectomy
