摘要
目的:探讨老年急性髓系白血病(AML)化疗方案。方法:选择我院2001-06～2011-06收治的老年AML患者(>60岁)64例进行分析,按照治疗方案分为2组,A组(亚标准剂量组),B组(预激方案组),并对2组患者疗效进行比较。结果:只有58例可进入疗效评价。A组33例,15例获完全缓解(CR),CR率为45.5%,B组25例,10例获CR,CR率为40.0%,2组CR率比较无统计学意义(P>0.05)。结论:亚标准剂量组相对老年患者而言化疗剂量较大,治疗相关病死率增加。减低剂量的CAG预激方案对老年AML患者来说有一个好的缓解率及总生存时间。
Objective：To explore the chemotherapy strategy in elderly patients with acute myelogenous leukemia（AML）.Methods： A total of 64 patients aged 60 years with AML from 2001 to 2011 were analyzed,the patients were divided into two groups,group A（substandard-dose regimen group,n=33）,group B（preexcitation regimen group,n=25）.The therapeutic effect of the patients were compared.Results： Only 58 patients entered into our study.The complete remission（CR） of group A and B was 45.5 % and 40.0 % respectively.There was no significant difference in CR rate between the two groups（P0.05）.Conclusion： The chemotherapy dose of substandard-dose regimen group is excessive to elderly patients,the treatment related mortality is increased.The remission rate and total survival time is better in low dose preexcitation regimen group.
出处
《西北国防医学杂志》
CAS
2012年第5期522-524,共3页
Medical Journal of National Defending Forces in Northwest China
关键词
白血病
髓细胞性
急性
化疗
老年
Leukemia
Myelocyte
Acute
Chemotherapy
Elderly
