摘要
本文20例原发性血小板减少性紫癜进行了抗血小板膜糖蛋白GPⅡb/Ⅲa抗体测定,结果25％为阳性,提示患者血浆中抗体是不均一的。有些患者抗体的部位是作用于GPⅡb/Ⅲa的位置上。同时,对12例急性ITP进行了80人次连续血小板数及血小板平均容积(MPV)的观察,发现二者有明显负相关,r=一0.96,P值<0.01。结果提示MPV大小与血小板年龄无关。
An ELISA method was established to detect the autoantibodies to GPⅡb/ Ⅲa in ITP plasma. In the plasma from 20 ITP patients, 5 gave positive result,indicating the presence of anti-GPⅡb/ Ⅲa autoantibodies. This result, suggested that in plasma from some ITP patients (25%), there were autoantibodies to GPⅢb/Ⅱa which might recognise different antigenic sites of GPⅢb/Ⅲa.At the same time. the platelet number and platelet volume were measured by Hematology Series 810 Platelet Analyser from, 12 ITP patients for 80 person-time. It was found that there is aninverse relation-ship between platelet number and volume, r=-0.96, p value 0.01. It suggested that platelet size did not correlate with platelet age in ITP.
出处
《军医进修学院学报》
1990年第1期8-9,共2页
Academic Journal of Pla Postgraduate Medical School
