摘要
[目的]研究黄花铁线莲乙酸乙酯组分的抗炎作用。[方法]将试验动物随机分为4组,每组10只,分别为模型对照组、复方七叶皂苷钠凝胶组和黄花铁线莲高、低剂量组(0.08和0.04 g/kg),连续外涂给药7 d,采用二甲苯诱发小鼠耳肿胀法和交叉菜胶诱发大鼠足跖肿胀观察抗炎作用。[结果]黄花铁线莲乙酸乙酯组分可以明显抑制二甲苯诱发小鼠耳肿胀和交叉菜胶诱发大鼠足跖肿胀。[结论]黄花铁线莲乙酸乙酯组分具有良好的抗炎活性。
[Objective] To study the anti-inflammatory effect of ethylacetate extract from Clematis intricata Bunge.[Method] The animals were randomly divided into four groups,ten each group,including the control group,compound sodium aescinate gel group,low and high dose of Clematis intricata Bunge group（at doses of 0.08 and 0.04 g/kg accordingly） for 7 days.Model of ear swelling in mice and model of paw edema in rats were adopted to observe the anti-inflammatory effect.[Result] The ethylacetate extract from Clematis intricata Bunge could significantly decrease the raw edema and inhibit the ear edema.[Conclusion] Ethylacetate extract from Clematis intricata Bunge has obvious anti-inflammation.
出处
《安徽农业科学》
CAS
2012年第29期14231-14231,14262,共2页
Journal of Anhui Agricultural Sciences
基金
陕西省教育厅自然科学基金资助项目(No.2010JK912)
关键词
黄花铁线莲
抗炎作用
Clematis intricata Bunge
Anti-inflammation effect
