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左氧氟沙星不良反应报告分析 被引量:10

Analysis of ADR Reports of Levofloxacin
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摘要 目的分析左氧氟沙星不良反应及特点,促进合理用药。方法收集台州市椒江区不良反应监测中心2010年1月—2011年12月的不良反应报告,共发生左氧氟沙星注射液不良反应135例,回顾性分析左氧氟沙星不良反应患者的性别、年龄、既往史、日剂量、用药途径、临床表现等。结果 135例不良反应报告中,给药途径以静脉滴注为主,有130例(96.3%);不良反应表现以皮肤及附件损害为主,有102例(63.0%),其次为消化系统损害,有17例(10.5%)。结论应加强左氧氟沙星不良反应监测,掌握其相关因素及临床表现,促进合理用药。 Objective To analyse adverse reactions of levofloxacin and characteristics, and promote rational drug use. Methods Collect taizhou Jiaojiang adverse reaction monitoring center in January 2010-December 2011 adverse reactions report, a total of levofloxacin injection adverse reaction occurred in 135 cases. By retrospective study 135 ADR reports of levofloxacin from gender, age, past history, daily dose, route of administration, clinical manifestation, etc. Results Of the total 135 cases, 130 (96. 3% ) cases were induced by intravenous injection, 102 (63.0%) cases were adverse reaction to damage to the skin and accessories mainly, followed by the digestive system damage, 17 (10. 5% ) cases. Conclusion Should strengthen the monitoring of adverse reactions of levofloxacin, master the related factors and clinical manifestation of levofloxacin, promote rational drug use.
作者 张敏红
出处 《临床合理用药杂志》 2012年第30期29-30,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 左氧氟沙星 不良反应 分析 Levofloxacin Adverse reactions Analysis
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