摘要
目的探讨卡培他滨治疗老年晚期胃癌术后的临床效果及不良反应情况。方法回顾性分析38例应用卡培他滨治疗的老年晚期胃癌术后进展期患者的临床资料,评价其临床疗效和不良反应。结果所有患者均完成4～6周期化疗,总有效率为47.37%(18/38)。不良反应主要为Ⅰ或Ⅱ级手足综合征,停药或对症处理后均能好转或消失。结论口服卡培他滨治疗老年晚期胃癌使用方便、疗效确切,不良反应较少,值得临床推广应用。
Objective Observe the clinical effect and adverse reactions of Capecitabine in the treatment of elderly patients with advanced gastric cancer. Methods Retrospective analysis of 38 cases of elderly patients with advanced gastric cancer after surgery treated by Capecitabine to evaluate the clinical efficacy and adverse reactions. Results All patients had finished 4 to 6 cycles of chemotherapy. The total effective rate was 47.37% （18/38）. The main adverse reactions was I or U level hand- foot syndrome, it can be improved or disappeared after the withdrawal or symptomatic treatment. Conclusion Oral Capecitabine treatment of elderly patients with advanced gastric cancer is convenient, effective, and has less adverse reactions. It is worthy of clinical application.
出处
《肿瘤药学》
CAS
2012年第5期379-380,384,共3页
Anti-Tumor Pharmacy
关键词
卡培他滨
老年
晚期胃癌
Capecitabine
Elderly
Advanced gastric carcinoma
