期刊文献+

17例纤维板层型肝癌临床分析 被引量:2

Clinical analysis of 17 cases of fibrolamellar hepatocarcinoma
暂未订购
导出
摘要 目的:探讨纤维板层型肝癌的发病特点、临床症状、实验室检查、影像表现、病理特征、治疗方法及生存时间。方法:结合近年文献,回顾性分析17例确诊为纤维板层型肝癌患者的临床资料。结果:发现17例患者9例为中青年人(年龄在45岁以下)占58.8%,其临床表现和体征不明显,实验室检查基本正常,影像表现为单个结节,手术切除率高,3年和5年生存率分别达到76.5%和58.5%。结论:纤维板层型肝癌主要病理特点为纤维板层基质和强嗜酸性颗粒,好发于青年人,症状轻,与乙型肝炎无正相关联,临床进展慢,预后好。 Objective:To investigate the clinical features,laboratory test results,imaging findings,pathological characteristics,treatment and survival time of the fibrolamellar hepatocarcinoma.Methods:To analyze the clinical data of 17 patients diagnosed as fibrolamellar hepatocarcinoma.Results:Among the 17 patients with fibrolamellar hepatocarcinoma,9 patients were under 45 years old.The fibrolamellar hepatocarcinoma has no obvious clinical manifestations and signs,with approximate normal laboratory test results,showed only a single nodule in image,it was relatively easy removed by surgery,and the survival time of 3 years and 5 years were 76.5% and 58.5%.Conclusion:The fibrolamellar hepatocarcinoma was common in young person,its characteristic pathological feature was with lamellar fiber matrix and strong eosinophilic granular,with mild clinical symptoms,had no obvious relationship with HBV,with relatively slow clinical progression,and good prognosis.
机构地区 解放军第
出处 《现代肿瘤医学》 CAS 2012年第10期2112-2113,共2页 Journal of Modern Oncology
关键词 纤维板层型肝癌 临床分析 病理特点 fibrolamellar carcinoma of liver clinical feature characteristic pathologica
  • 相关文献

参考文献9

  • 1Teitelbaum DH, Tuttle S, Carey LC, et al. Fibrolamellar carcinoma of the liver. Review of three cases and the presentation of a charac- teristic set of tumor markers defining this tumor [ J ]. Ann Surg, 1985,202( 1 ) :36 -4l.
  • 2罗彦英,高玉彤,潘彦珞,谭郁彬,张乃馨.纤维板层型肝细胞癌1例报道及文献复习[J].中国肿瘤临床,2005,32(4):209-211. 被引量:8
  • 3薛卫成,冷希圣,阚秀,回允中.纤维板层型肝细胞癌的临床及病理特征[J].中华普通外科杂志,2000,15(1):57-58. 被引量:8
  • 4Blachar A, Federle MP, Ferris JV, et al. Radiologists performance in the diagnosis of liver tumors with central scars by using specific CT criteria [ J ]. Badiology ,2002,223 (2) :532 - 539.
  • 5贾户亮,钦伦秀.影响肝癌预后的临床相关因素[J].肿瘤,2002,22(1):76-79. 被引量:15
  • 6邱雍,蔡刁龙.纤维板层型肝细胞癌2例临床分析[J].临床和实验医学杂志,2009,8(8):23-24. 被引量:3
  • 7陈崇彬,石群立,孙桂勤.肝纤维板层型癌1例[J].金陵医学报,1999,12(1):53.
  • 8Kakar S, Burgart LJ, Batts KP, et al. Clinicopathologic features and survival in fibrolamellar carcinoma: comparison with conventional hepatocellular carcinoma with and without cirrhosis [ J ]. Mod Patho1,2005,18 ( 11 ) : 1417 - 1423.
  • 9Moreno - Luna LE, Arrieta O, Garcia - Leiva J, et al. Clinical and pathologic factors associated with survival in young adult patients with fibrolamellar hepatocarcinoma[ J ]. BMC Cancer,2005,5 : 142.

二级参考文献16

  • 1樊嘉,余业勤.纤维板层型肝癌三例报告[J].中华外科杂志,1995,33(8):469-469. 被引量:2
  • 2袁丁,李波.纤维板层型肝细胞癌的研究进展[J].华西医学,2006,21(3):651-652. 被引量:6
  • 3丁洪基 李新功.肝纤维板层癌一例[J].中华肿瘤杂志,1996,18:78-78.
  • 4任正刚,杨秉辉,叶胜龙,张炜.雌激素受体与原发性肝癌生物学特性的关系[J].中华肿瘤杂志,1997,19(1):10-13. 被引量:15
  • 5袁永胜,王滨,张献忠,王洪波.纤维板层型肝癌二例报告[J].实用癌症杂志,1997,12(1):78-79. 被引量:2
  • 6Saab S, Yao F. Fibrolamellar hepatocellular carcinoma. Case reports and a review of the literature [J]. Dig Dis Sci, 1996, 41(10):1981 ~1985.
  • 7Saul SH. The fibrolamellar variant of hepatocellular carcinoma: its association with focal nodular hyperplasia [J]. Cancer, 1987, 60(12): 3049 ~3055.
  • 8Vecchio FM, Fabiano A, Ghirlanda G, et al. Fibrolamellar carcinoma of the liver: The malignant counterpart of Focal nodular hyperplasia with oncocytic change [J]. AmJ Clin Pathol, 1984, 81(4): 521~526.
  • 9Saab S,Dig Dis Sci,1996年,41卷,1981页
  • 10丁洪基,中华肿瘤杂志,1996年,18卷,78页

共引文献25

同被引文献15

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部