摘要
腹腔感染是急性重症胰腺炎死亡的主要原因。目前认为感染来源于肠粘膜屏障受损所导致的细菌移位 ,但肠粘膜屏障受损的机制尚不清楚。本文综合了肠粘膜屏障受损的可能原因 ,重点讨论了重症胰腺炎时细胞因子对肠粘膜屏障的影响和肠粘膜屏障的变化 。
Intraabdominal sepsis is now the leading cause of mortality after acute severe pancreatitis, the source of pathogenic bacteria is from the gut, gut mucosal barrier function is impaired after acute severe pancreatitis but the mechanisms of impairment are unknown. The article reviewed the possible mechanisms of injury and special attentions were paid to the roles of cytokines and the changes of gut mucosal barrier function, strategies against sepsis were also raised.
出处
《医学研究生学报》
CAS
2000年第3期185-189,共5页
Journal of Medical Postgraduates
关键词
胰腺炎
细菌移位
腹腔感染
病理
防治
Pancreatitis
Bacterial translocation
Intraabdominal infection
