摘要
目的研究黄杞(Engelhardtia roxburghiana wall.)叶的化学成分。方法黄杞叶经溶剂提取和萃取粗分后,用硅胶柱色谱法分离单体成分,用1H-NMR,13C-NMR,MS等方法鉴定结构。结果从黄杞叶中分离并鉴定了13个化合物:花旗松素(1),5,7,4'-三羟基二氢黄酮(2),山柰酚(3),二氢山柰酚(4),槲皮素(5),异黄杞苷(6),黄杞苷(7),落新妇苷(8),异落新妇苷(9),山柰酚-3-O-α-L-鼠李糖苷(10),5,7-二羟基色原酮-3-O-α-L-吡喃鼠李糖苷(11),5-羟基-3,7,3',4'-四甲氧基黄酮(12),槲皮素-3-O-α-L-吡喃鼠李糖苷(13)。结论化合物2,4,9,11,12为首次从该植物中分离得到。
OBJECTIVE To investigate the chemical constituents of the leaves of Engelhardtia roxburghiana. METHODS Af- ter the plant materials were extracted and fractionated with solvents, column chromatography was used to isolate and purify the compounds. The structures were elucidated on the basis of 1H-NMR, 13 C-NMR, MS analysis and comparison with the literature data. RESULTS Thirteen compounds were identified as following ： taxilfolin （ 1 ）, 5,7,4＇-trihydroxy flavanone （ 2 ）, kaempferol （ 3 ）, dihydrokaempferol （4）, quercetin （ 5 ）, isoengeletin （ 6 ）, engeletin （ 7 ）, astilbin （ 8 ） , isoastilbin （ 9 ）, kaempferol-3-O-a-L-rhamnoside （ 10 ）, eucryphin（ 11 ）, 5-hydroxy-3 ,7 ,3＇ ,4＇-tetramethoxyflavone（ 12）, quercetin-3-O-a-L-rhamnoside（13）. CONCLUSION Compounds2, 4, 9, 11 and 12 were identified from the title plant for the first time.
出处
《中国药学杂志》
CAS
CSCD
北大核心
2012年第20期1617-1620,共4页
Chinese Pharmaceutical Journal
基金
重大新药创制科技重大专项(2009ZX09308)
关键词
黄杞
化学成分
二氢黄酮
黄酮
5
7
4’-三羟基二氢黄酮
二氢山柰酚
异落新妇苷
Engelhardtia roxburghiana
chemical constituent
dihydroflavone
flavone
5,7,4＇-trihydroxy flavanone
dihydro- kaempferol
isoastilbin
