摘要
目的 探讨情感性障碍患者病前病后所生子女的易患效应。方法 对符合国际疾病分类第 10版和中国精神疾病分类方案的诊断标准第 2版修订本中情感性精神障碍诊断的 10 2个先证者家系登门调查 ,收集子女发病与父母患病前后所生子女的有关资料。结果 父方患病 6 9个家系 ,母方患病 33个家系 ,共生子女为 2 86人 ,相关资料完整可供研究的子女2 78人 ,其中患情感障碍者 2 6人。从父母任一方患病前后所生、父方患病前后所生、母方患病前后所生子女及儿子、女儿性别等几个方面分别进行了相关分析。结论 情感障碍患者子女患者与其父母患病前后所生无关。
To explore the Susceptlbilites of offsprings of patients with affective disorder who were born before and after onset.Methods:102 probands with afftective disorder were diagnosed with the 10 th edition of International Classification of Diseases and Chinese Classification and Diagnostic Criteria for Mental Disorder.The data of offsprings of the probands were collected.Results: There were 69 paternal probands and 38 maternal probands in the 102 pedgrees. They had 286 offsprings.278 of them had been studied. 26 offsprings suffered from affective disorder.Correlative analyses were made between before and after onset,paternal probands and maternal ones,and male offsprings and female ones. Conclusion:There was no difference in the susceptibilities between offsprings born before onset and those born after it.
出处
《中国优生与遗传杂志》
2000年第3期136-137,84,共3页
Chinese Journal of Birth Health & Heredity
关键词
情感障碍
遗传学
子女易患效应
Affective disorder, Genetics,Offspring,Susceptibility.
