摘要
目的:探讨卵巢硬化性间质瘤的临床表现、病理特点及诊断。方法:介绍本院收治的1例卵巢硬化性间质瘤合并腹水患者,分析其主要临床表现、影像学及病理特点,并复习相关文献。结果:本病临床表现主要为月经不规律、原发或继发不孕、腹痛、盆腔包块、腹水。绝经后妇女可出现阴道出血。彩色多普勒超声发现肿瘤周边实性部分可检出较丰富的血流信号,CT对比增强扫描显示动脉期病灶周边强化明显,并向中心扩充,静脉期病灶强化仍明显,呈"快进慢出"特征,颇似"肝海绵状血管瘤"。镜下主要特征是间质瘤内区域性进行性硬化性胶原变性,瘤细胞形态多样,形成假小叶结构,血管丰富,可见大片疏松水肿区。结论:B超和CT检查能协助诊断。对于有腹水、盆腔实性包块、阴道不规则出血的女性,应考虑该疾病可能。术中送冰冻病理检查,避免过度治疗。
Objective：To explore clinical manifestation,pathology characteristic and diagnosis of sclerosing stroreal tumor of the ovary.Methods：We introduced a 31-year-old female with sclerosing stromal tumor of the ovary with ascites treated in the hospital,reviewed literature and analyzed major clinical manifestation,neuroimaging characteristic and pathological characteristic.Results：Most patients with tumors presented with men- strual irregularities,primary or secondary infertility,pelvic pain,pelvic mass and ascites.Postmenopausal women maybe bleed.Color Doppler flow imaging of B mode ultrasound found tumor surrounding solid part can be de- tected with abundant blood flow signal.CT contrast enhancement scanning showed lesion surrounding marked enhancement and center expansion at arterial phase,and lesion marked enhancement at venous phase.lt ap- peared the characteristic as＂fast-in and slow-out＇just like＂hepatic cavermous hemangioma.Under microscope the major feature was regional progressive sclerosing collagenous degeneration inside the stromal tumor,the tu- mor cells various forms,forming false lobular structures with rich vascular and large evacuation edema area. Conclusion：B mode ultrasound could assist in diagnosis.Sclerosing stromal tumor should be considered in the females with ascites,pelvic solid mass,menstrual irregularities.Intraoperative fast frozing pathology should be used to avoid overtreatment.
出处
《中日友好医院学报》
2012年第5期268-271,F0004,共5页
Journal of China-Japan Friendship Hospital
关键词
硬化性间质瘤
卵巢肿瘤
sclerosing stromal tumor
ovarian neoplasm
