摘要
目的通过超声检测评价在中年2型糖尿病及合并高脂血症对下肢动脉粥样硬化的影响,探讨超声检测在该类疾病诊治中的应用价值。方法用彩色多普勒超声观察2型糖尿病患者53例、糖尿病合并高脂血症患者41例(下称合并症组)及非糖尿病住院的34例对照患者的下肢动脉内-中膜厚度及斑块发生部位,并计算斑块检出率。结果糖尿病组、合并症组患者斑块的检出率及下肢动脉内-中膜厚度,均显著高于对照组,合并症组的斑块检出率及内-中膜厚度值最高,差异有统计学意义(P〈005)。其中合并症组与糖尿病组比较,FBG、HbA。差异均无统计学意义(均P〉0.05)。讨论糖尿病及合并高脂血症可加重下肢动脉粥样硬化的程度,超声检查可以为临床提供可靠信息。
Objective To assess arteriosclerosis of lower extremities by ultrasonography in middle-aged type 2 diabetic patients with hyperfipidemia. Methods Forty one type 2 diabetic patients with hypedipidemia, 53 diabetic patients with normolipidemia and 34 normal subjects were enrolled in the study. Intima-media thickness (IMT) and plaque of lower extremity arteries were examined with color Doppler ultrasonography. Results The IMT and plaque detection rate in diabetes group and diabetes with hyperlipidemia group were significantly higher than those in control group (P〈0.05), particularly in superficial femoral artery, anterior tibial artery and dorsalis pedis artery. There were no significant differences in FBG, HbA1c levels between diabetic patients and diabetic patients complicated with hypedipedemia (P 〉0.05). Conclusion The degree of atherosclerosis of ower extremities is increased in diabetic patients complicated with hyperlipidemia, which can be assessed by ultrasonography.
出处
《浙江医学》
CAS
2012年第18期1497-1498,1502,共3页
Zhejiang Medical Journal
关键词
糖尿病
高脂血症
下肢动脉
动脉粥样硬化
超声
Diabetes Hyperlipidemia Extremity artery Atherosclerosis Ultrasonography