摘要
目的:了解我院门诊抗菌药物应用现状,为合理使用抗菌药物提供依据。方法:随机抽取我院2010年1—12月每月1天的门诊处方,共计13 162张,统计处方的用药品种、销售金额等,并统计抗菌药物处方中抗菌药物种类、名称、每日剂量、用药天数、给药途径、联合用药情况及抗菌药物分类使用情况等。以世界卫生组织(WHO)建议的限定日剂量(DDD)及药物利用指数(DUI)作为判断是否合理用药的标准。结果:抗菌药物使用率为27.98%,其销售金额占药品总销售金额的12.5%,单一抗菌药物使用率为87.48%,处方平均金额为233.87元。口服抗菌药物DUI排序前10位中有7种药品的DUI>1,注射用抗菌药物DUI排序前10位中有2种药品的DUI>1,其中6种口服药、1种注射用药是由于临床用药日剂量基本符合我国药品说明书规定日剂量但高于WHO的DDD所致。结论:我院门诊抗菌药物处方各项指标基本符合要求,除个别药品外,抗菌药物的应用基本符合我国药品说明书要求。
OBJECTIVE ： To investigate the utilization of antibiotics in the outpatient department of our hospital so as to provide references for rational use of antibiotics. METHODS： A total of 13 162 outpatient prescriptions （one day＇ s prescriptions monthly during Jan. -Dec. of 2010） were randomly sampled for statistical analysis with regard to drug varieties, consumption sum of drugs ; the names, daily dose, duration of antibiotic use, route of administration, classified use of antibiotics etc with defined daily dose （DDD） and drug utilization index （DUI） recommended by the WHO as evaluation criteria for rational drug use. RESULTS： The average rate of antibiotic use was 27.98% ; the antibiotics accounted for 12. 5% of total in terms of consumption sum; the rate of single use of antibiotics was 87.48% ; the average drug consumption sum per prescription was 233.87 yuan; DUI 〉 1 was seen in 7 of the top 10 oral antibacterial drugs ranked by DUI and in 2 of the top 10 antimicrobial drugs for injection ranked by DUI ; the daily dose in 6 of the oral antibacterial drugs and 1 of the antimicrobial drugs for injection was in line with the defined daily dose （DDD） defined in package inserts of China but higher than that recommended by WHO. CONCLUSION： The indicators of the outpatient prescriptions of antibiotics in our hospital were basically up to the standard; the use of all except a few antibiotics in our hospital was up to the standard specified in the package inserts of China.
出处
《中国医院用药评价与分析》
2012年第9期792-794,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
抗菌药物
门诊处方
药物利用
Antibiotics
Outpatient prescription
Drug utilization
