摘要
目的:统计2007—2011年卫生部北京医院中成药致不良反应发生的情况,提请临床用药注意,促进临床合理用药。方法:采用自发呈报的方式,由临床医师、护士及临床药师填写药品不良反应(ADR)报表,收集2007—2011年卫生部北京医院155例中成药不良反应报告,从患者年龄、不良反应品种及表现、累及器官和(或)系统、预后等方面进行统计、分析。结果:155例中成药不良反应中,60岁以上老年患者共58例(占37.4%);小金丸引起不良反应例数最多,共29例(占18.7%);临床表现以皮肤及附件损害最常见,共90例(占58.1%)。结论:应辨证看待中成药的ADR,加强ADR监测工作,避免或减少ADR发生,使中成药的使用更加合理。
OBJECTIVE：To review the adverse drug reaction （ADR） induced by Chinese traditional patent medicine in Beijing Hospital of Ministry of Health during 2007-2011 to arouse clinical attention on drug use in an attempt to promote rational drug use. METHODS： By voluntary reporting, the ADR report forms were filled in by clinicians, nurses and clinical pharmacists, and a total of 155 ADR cases induced by Chinese traditional patent medicines collected in Beijing Hospital of Ministry of Health during 2007-2011 were analyzed statistically in terms of patients＇ age, drug varieties, ADR manifestation, organs and （or） systems involved and prognosis etc. RESULTS： Of the total 155 ADR case, 58 （37.4%） were patients aged above 60 years; 29 （18.7%） were induced by Xiao-jin pills; 90 （58.1%） manifested as lesions of skin and its appendants. CONCLUSION： The ADR induced by Chinese traditional patent medicine should be viewed dialectically. It is necessary to tighten ADR monitoring to avoid or reduce ADR incidence and achieve more rational use of Chinese traditional patent medicine.
出处
《中国医院用药评价与分析》
2012年第8期741-744,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
中成药
不良反应
安全监测
Chinese traditional patent medicine
Adverse drug reaction
Safety monitoring
