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围产期生殖道支原体感染与新生儿肺炎关系的前瞻性研究 被引量:3

A prospective study on the relationship between neonatal pneumonia and genital mycoplasma infection during perinatal period
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摘要 为了探讨围产期生殖道支原体感染与新生儿肺炎的关系,本研究随机入选739名孕妇,采用支原体培养法检测围产期阴道解脲支原体(Uu)和人型支原体(Mh),根据检测结果分为支原体阳性组和支原体阴性组,随访观察两组新生儿肺炎发生率。研究显示支原体阳性组247例,支原体阴性组492例,两组新生儿肺炎发生率无显著性差异;进一步分组研究发现Mh(+)Uu(-)亚组新生儿肺炎发生率显著高于支原体阴性组(11.5%对2.2%,RR5.16,95%CI 1.99~13.38,P<0.05)。提示围产期生殖道Mh感染可能导致新生儿肺炎的发生。 To explore the relationship between neonatal pneumonia and genital mycoplasma infection during perinatal period, vaginal ureaplasma urealyticum (Uu) and mycoplasma hotninis (Mh) were detected by the method of mycoplasma culture in 739 pregnant women who were randomly enrolled into the study. They were divided into the positive group (n = 247) and the negative group (n = 492) based on the results of mycoplasma culture. The incidences of neonatal pneumonia in these pregnant women's babies were compared between two groups. The results showed that no significant difference in the morbidity of neonatal pneumonia was observed between two groups. The further study showed that the incidence of neonatal pneumonia in pregnant women with Mh( + )Uu( -)was significantly higher than that in pregnant women with Mh( -)Uu (-)(11. 5% vs. 2. 2%, RR = 5.16,95% CI = 1. 99-13. 38, P<0. 05). It is concluded that Mh infection during perinatal period may play an important role in the occurrence of neonatal pneumonia.
出处 《临床儿科杂志》 CAS CSCD 北大核心 2000年第3期162-163,共2页 Journal of Clinical Pediatrics
基金 国家自然科学基金 编号39670646
关键词 生殖道 支原体感染 围产期 新生儿肺炎 相关性 mycoplasma infection perinatal period neonatal pneumonia
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参考文献5

  • 1Cassell GH,Waites KB,Crouse DT.Perinatal mycoplasma infection.Clin Perinatol,1991,18(2):241.
  • 2David A,Eschenbach MD.Ureaplasma urealyticum as a cause of postpartum fever.Pediatr Infect Dis,1986,5:256.
  • 3Carey JC,Blackwelder WC,Nugent RP,et al.Antepartum cultures for ureaplasma urealytium are not useful in predicting pregnancy outcomes.The vaginal infections and prematurhy study group.Am J Obstet Gynecol,1991,164(4):728.
  • 4Quinn PA,Gilla JE,Markestad T,et al.Intrauterine infenion with ureaplasma urealyticum as a cause of fatal neonatal pneumonia.Pediatr Infect Dis,1985,4(5):538.
  • 5Embree JE,Krause VW,Embil JA,et al.Placental infection with mycoplasm hominis and ureaplasma urealyticum:clinical correlation.Obstet Gynecol,1980,56(4):465.

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