摘要
目的探索盐酸氨溴索与黄芪注射液治疗慢性阻塞性肺疾病的临床疗效。方法将120例慢性阻塞性肺气肿患者随机分为两组,对照组给予常规治疗,实验组在常规治疗基础上加用盐酸氨溴索与黄芪注射液,检测并比较两组患者的动脉血气分析指标[动脉血氧饱和度(SaO2)、动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、血红蛋白(Hbg)、用力肺活量(FVC)以及第1秒用力呼气容积百分比(FEV1%)]和临床疗效。结果实验组SaO2(t=4.839,P=0.000)、PaO2(t=3.521,P=0.001)、FVC(t=2.717,P=0.008)、FEV1%(t=4.555,P=0.000)高于对照组,而PaCO2(t=3.452,P=0.001)、Hbg(t=4.783,P=0.000)低于对照组。实验组临床疗效也优于对照组(Z=2.550,P=0.011),实验组有效率为95%,对照组有效率为85%。结论盐酸氨溴索和黄芪注射液治疗方案临床疗效好,在慢性阻塞性肺气肿患者的临床治疗中有较高的应用价值。
Objective To evaluate the clinical effect of Chinese and Western medicine combination of mucosolvan and astragalus injection for treating chronic obstructive pulmonary disease（COPD）.Methods 120 patients of chronic obstructive pulmonary emphysema were randomly allocated into two groups.The control group was given ordinary treatment.The experiment group was given ordinary treatment plus mucosolvan and astragalus injection.The results of arterial blood gas analysis and the clinical effects were measured and compared between the two groups.Results The level of SaO2（t=4.839,P=0.000）,PaO2（t=3.521,P=0.001）,FVC（t=2.717,P=0.008）,FEV1%（t=4.555,P=0.000）in the experiment group were high than those in the control group, but PaCO2（t=3.452,P=0.001）and Hbg（t=4.783,P=0.000） were lower than those in the control group.The clinical effect in the experiment group was superior to the control group（Z=2.550,P=0.011）.The effective rates in the experiment and control group were 95% and 85%,respectively.Conclusion The therapeutical regimen of mucosolvan and astragalus injection has good clinical effect and the higher application value for the treatment of chronic obstructive pulmonary emphysema
出处
《现代医药卫生》
2012年第18期2724-2725,共2页
Journal of Modern Medicine & Health
关键词
肺疾病
阻塞性/中西医结合疗法
慢性病
氨溴索/治疗应用
黄芪/治疗应用
注射剂
Lung diseases,obstructive/zhong xi yi jie he liao fa
Chronic disease
Ambroxol/therapeutic use
Astragalus membranaceus/therapeutic use
Injectio
