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13号染色体缺失与多发性骨髓瘤预后相关性的研究

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摘要 多发性骨髓瘤（multiple myeloma,MM）是以浆细胞异常增生为特征的一种恶性肿瘤疾病,占血液系统肿瘤的10%、全身恶性肿瘤的1%。好发于中老年人,近年来由于我国人口老龄化及人们对该病的认识水平提高,该病发病率有逐渐增加趋势。染色体异常是MM预后的重要指标,
作者 徐洪伟 贺飞
机构地区 哈尔滨医科大学附属第二医院检验科
出处 《中国实验诊断学》 2012年第9期1722-1724,共3页 Chinese Journal of Laboratory Diagnosis
关键词 多发性骨髓瘤 预后相关性 13号染色体缺失 浆细胞异常增生 人口老龄化 染色体异常 肿瘤疾病 中老年人
分类号 R733.3 [医药卫生—肿瘤]
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参考文献8

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二级参考文献10

  • 1SHAUGHNESSY J,TIAN E,SAWYER J,et al.Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization-defined chromosome 13 deletion in muhiple myeloma:early results of total therapy II[J].Br J Haematol,2003,120:44-52.
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  • 9罗绍凯,苏畅,王晓桃,李娟.102例多发性骨髓瘤临床资料分析[J].临床血液学杂志,2008,21(2):115-116. 被引量：12
  • 10葛祥花.多发性骨髓瘤患者血清β_2-微球蛋白、C反应蛋白水平的测定及临床意义[J].临床血液学杂志,2003,16(5):242-243. 被引量：18

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中国实验诊断学
2012年 第9期

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