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糖皮质激素及瘦素与胰岛素抵抗的关系

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摘要 胰岛素抵抗(Insulin Resistance,IR)是指机体对一定量(一定浓度)胰岛素的生物效应降低,主要指机体胰岛素介导的葡萄糖摄取和代谢能力降低,包括胰岛素的敏感性和反应性下降。IR可发生于组织器官水平(骨骼肌、脂肪、肝脏和血管内皮),也可发生于亚细胞及分子水平(胰岛素受体前、受体及受体后)。糖皮质激素是重要的胰岛素拮抗激素.
作者 郭小勇 杜群
出处 《包头医学院学报》 CAS 2012年第4期128-129,共2页 Journal of Baotou Medical College
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参考文献12

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