摘要
目的利用经胸超声心动图探讨肺动脉顺应性指数(pulmonary arterial compliance index,PACI)评价行室间隔缺损(ventricular septal defect,VSD)封堵术患者肺动脉顺应性的价值,分析PACI与患者年龄及术后肺动脉收缩压(pulmonary arterial systolic pressure,PASP)变化的相关性。方法选取适合介入封堵治疗的膜周部VSD患者74例,根据年龄分为>40岁组、20～40岁组与<20岁组,根据术后PASP值分为>40 mm Hg组、30～40 mm Hg组与<30mm Hg组,74例患者术前均采用超声心动图测量缺损直径、跨缺损分流压差与PASP,计算VSD面积指数与PACI,术后3个月再次测量PASP,并进行分析及对比。结果 >40岁组术前PACI明显低于20～40岁组与<20岁组,术后PASP高于20～40岁组与<20岁组,差异有统计学意义(P<0.05),3组VSD面积指数比较差异无统计学意义(P>0.05);术后PASP>40 mm Hg组PACI低于30～40 mm Hg组与<30 mm Hg组,VSD面积指数高于30～40mm Hg组与<30mm Hg组,差异有统计学意义(P<0.05)。结论 VSD患者术后PASP的恢复与年龄及PACI相关,PACI可作为评价行VSD封堵术患者PASP恢复程度的指标之一。
Objective To assess the value of pulmonary arterial compliance index （PACI） on transthoracic echocardlogram to the evalucation of pulmonary arterial compliance after ventricular septal defect （VSD） closure, and explore the correlation of PACI with age and changes in pulmonary arterial systolic pressure （PASP） after operation. Methods A total of 74 patients with membranous VSD suitable for interventional occlusion were divided into 〉40-year- old group, 20-to-40-year-old group and %20-year-old group according to age before operation, and into 〉40 mm Hg group, 30 to 40 mm Hg group and %30 mm Hg group according to PASP after operation. The echocardiography was used to measure the ventricular septal defect diameter, differential pressure across the shunt defect and PASP to calculate ventricular septal defect area index （VSD-Ai） and PACI before operation. The PASP was measured, analyzed and compared three months after operation. Results PACI was lower before operation and PASP was higher after operation in 〉40-year-old group than that in the other two groups, which showed a significant difference （P〈0.05）. There was no significant difference in VSD-Ai among these three groups （P 〉 0.05）. PACI was lower and VSD-Ai was higher in 〉40 mm Hg group than that in the other two groups after operation, which showed a significant difference （P〈 0.05）. Conclusion The restoration of PASP after operation is closely correlated with age and PACI in patients with VSD. PACI can be used as one of the indicators to evaluate the PASP recovery degree after percutaneous closure.
出处
《中华实用诊断与治疗杂志》
2012年第10期984-986,共3页
Journal of Chinese Practical Diagnosis and Therapy
关键词
超声心动描记术
室间隔缺损
肺动脉顺应性
肺动脉收缩压
Echocardiographyl ventricular septal defect
pulmonary arterial compliance
pulmonary artery systolic pressure
