摘要
目的分析超声造影(CEUS)量化分析在原发性肝细胞癌(HCC)介入治疗后残存血供评价中的应用价值。方法对2008年1月～2012年1月来本院进行治疗的60例HCC患者共66个病灶进行经导管肝动脉化疗栓塞(TACE)和超声引导下95%医用乙醇消融(PEI)治疗,应用低机械指数状态下CEUS评价疗效;使用软件检测残留灶内血流灌注信息,并进行时间-强度量化分析。结果 CEUS时间-强度量化分析显示有6个病灶完全灭活,治疗前瘤体直径均在3 cm以下;60个残留灶增强强度及时间均无显著变化(P>0.05),但治疗前后曲线下面积差异显著,有统计学意义(P<0.05)。结论 CEUS量化分析能够准确显示HCC经TACE/PEI治疗后的坏死范围,有助于对残留肿瘤血供的客观评价。
Objective To evaluate the value of the contrast enhanced ultrasound （CEUS） to quantify the residual blood in the interventional treatment of primary liver cancer. Methods Sixty HCC patients from January 2008 to January 2012 in our hospital were chosen, 66 lesions undergoing TACE and ultrasound-guided ethanol ablation therapy, then the effect was evaluated by state of low mechanical＇index real-time the CEUS; residual tumor perfusion information was detected in time-strength quantitative analysis by software. Results The analysis of CEUS time-strength quantify six lesions with thorough treatment which diameter was less than 3 cm; enhancement intensity and time of 60 residual tumor lesions did not change significantly （P 〉 0.05 ）, but the area under the curve was significantly different before and after treatment （ P 〈 0.05）. Conclusion CEUS quantitative analysis can accurately display the necrotic area of the HCC after treatment of the TACE/PEI, contribute to the objective evaluation for residual tumor blood supply.
出处
《哈尔滨医科大学学报》
CAS
北大核心
2012年第4期379-381,共3页
Journal of Harbin Medical University
关键词
超声造影
原发性肝癌
介入
肝细胞
contrast enhanced ultrasound
primary liver cancer
intervention
hepatocytes
