摘要
目的探讨药物性急性肾损伤(cute kidney injure,AKI)的原因和预后,提高诊治水平。方法对我院收治的115例药物性AKI的临床资料进行回顾性分析。结果引起药物性AKI的主要药物是抗生素,危险因素是高龄,诱因是脱水。本组55例采取保守治疗,60例行血液透析,治愈率为92.2%(106/115),无死亡病例。肾功能恢复正常时间平均为24.5 d。结论药物是造成AKI的常见原因,肾活检是确诊的重要手段,透析在AKI的治疗中有重要地位,可以改善预后。
Objective To explore the cause and prognosis of the phallic acute kidney injury （AKI） in order to improve therapeutic level. Methods Retrospective analysis of clinical data of 115 patients with pharmic AKI were performed. Results Antibiotic was the primary pathogen, old age was the risk factor, and dehydration was the incentive for AKI. 55 cases were given expectant treatment and 60 cases were treated with hemodialysis therapy. The cure rate of antibiotic-induced AKI was 92.2% （106/115）. No death occurred. The average time of nephric functional rehabilitation was 24.5 days. Conclusion The common cause for AKI is drugs. Renal biopsy is the most important method for diagnosis, and dialysis can improve prognosis in treating AKI.
出处
《解放军医药杂志》
CAS
2012年第9期48-50,共3页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
关键词
肾疾病
药用制剂
活组织检查
肾透析
Kidney diseases
Pharmaceutical preparations
Biopsy
Renal dialysis
