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帕金森病运动并发症的治疗策略与挑战 被引量:19

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摘要 帕金森病(Parkinson disease,PD)是中老年人以运动障碍为特点的神经系统变性疾病。随着全球人口的老龄化,PD患病人群不断上升,目前已成为危害中老年生活和健康的重要社会和医学问题。左旋多巴一直是PD药物治疗的金标准,患者在接受左旋多巴治疗的2~5年间其运动症状可得到有效控制和改善,但约70%~80%的患者于左旋多巴治疗后的5~10年间出现运动并发症(症状波动和异动症),发病年龄轻(〈60岁)的患者更容易出现Ⅲ。
作者 刘振国 万赢
出处 《中国神经免疫学和神经病学杂志》 CAS 北大核心 2012年第5期328-331,共4页 Chinese Journal of Neuroimmunology and Neurology
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