血清胱抑素C测定在新生儿肾功能早期损伤中的应用探讨被引量：1

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摘要目的探讨血清胱抑素C(Cys C)的检测在新生儿窒息后肾功能早期损伤中的临床应用。方法检测25例重度窒息组和35例轻度窒息组以及30例正常新生儿组血清中胱抑制素C,肌酐(Cr),尿素氮(BUN)的浓度,并比较分析三者的相关性及血清胱抑素C在新生儿窒息后肾脏早期损伤中的意义。结果①窒息两组的CysC、Cr、BUN皆比对照组升高。②轻度窒息组的CysC较正常对照组有显著性差异(P<0.05),重度窒息组较轻度窒息组有显著性差异(P<0.01)。③窒息组的Cys C与Cr、BUN有良好的正相关关系。结论血清胱抑素C的检测对于发现新生儿早期肾损伤的发现是一个良好的指标,并且其敏感性要高于Cr和BUN。三者的联合检测对于发现新生儿早期肾损伤具有重要的临床意义。

作者郑青青林洁

机构地区广东潮州市妇幼保健院

出处《中国医药指南》 2012年第25期223-224,共2页 Guide of China Medicine

关键词新生儿窒息血清胱抑素C 肾脏早期损伤

分类号 R722.12 [医药卫生—儿科]

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