摘要
目的分析并评价采用不同静脉麻醉药伍用芬太尼用于人工流产术的麻醉效果。方法随机将我院收治的要求终止妊娠的健康初次怀孕妇女122例分成观察组(依托咪酯+芬太尼)与对照组(异丙酚+芬太尼)各61例实施静脉麻醉,比较2组的麻醉效果、宫口松弛度、出血量以及并发症等指标,并对比分析术中2组孕妇的血压、呼吸、心率、术后呕吐、血氧饱和度以及苏醒时间等指数。结果观察组给药后呼吸频率稍减慢,血氧饱和度出现降低,未见血氧饱和度<90%者;对照组呼吸抑制作用明显,呼吸频率显著下降,44例患者血氧饱和度<90%,2组相比差异显著(P<0.01)。观察组给药后的心率、血流动力学、注射痛、呕吐以及肌颤人数与对照组相比差异显著(P均<0.01),均具有统计学意义。观察组的清醒时间均值为(10.0322±2.2432)min,长于对照组清醒时间均值(9.064±1.5725)min,但2组相比无明显差异(P>0.05),不具有统计学意义。结论依托咪酯具有确切的麻醉效果,对孕妇的呼吸及血压的影响轻微且无注射痛,而且对伴有呼吸系统或者心血管疾病的病人可能更加安全可靠。
Objective To analyze and evaluate the anesthetic effect of different intravenous anesthetic combined fentanyl for induced abortion. Methods Totally 122 cases of health pregnant women who required for termination of pregnancy were di- vided into observation group （etomidate and fentanyl） and control group （propofol and fentanyl） each of 61 cases; all patients were given the implementation of intravenous anesthesia. The indicators of the effects of anesthesia, degree of relaxation of the cervix, bleeding and complications were compared, and the relationship between the two groups of pregnant women＇s blood pressure, respiration, heart rate, postoperative vomiting, oxygen saturation, and wake time index were analyzed. Results Af- ter administration, respiratory rate was slightly slowed, the oxygen saturation slowed, but no oxygen saturation were less than 90 %. In the control group, respiratory depressed significantly, respiratory rate decreased significantly in 44 patients, oxygen saturation was less than 90%, which had significant difference between the two groups （P〈0.01）. After administration, the heart rate, hemodynamics, injection pain, vomiting, and the number of twitch in the observation group had significant differ- ence compared with control group （P〈 0.01）. The average awake time of observation group was （10.03 ± 2.24） minutes, which was longer than the mean awake time of the control group （9.06 ± 1.57） minutes, which showed no significant difference between the two groups （P〉0.05）. Conclusion Etomidate has an exact effect of anesthesia, and a negligible effect on the breathing and blood pressure in pregnant women and injection pain, and may be more safe and reliable for the patients with re- spiratory or cardiovascular disease.
出处
《中国实用神经疾病杂志》
2012年第18期18-19,共2页
Chinese Journal of Practical Nervous Diseases
