摘要
目的观察氨氯地平联合阿托伐他汀钙、氢氯噻嗪治疗以舒张压升高为表现的高血压病(2级高危组)临床观察。方法将高血压病(2级高危组)患者随机分为两组,观察组30例在使用氨氯地平片5mgqd联合使用用阿托伐他汀钙20mgqd、氢氯噻嗪片25mgqd,对照组25例给予氨氯地平5mgqd联合氢氯噻嗪片25mgqd。分别动态观察病人8周血压有效率及不良反应。结果观察组有30例有效,有效率100%;对照组有21例有效,有效率84%,观察组有效率高于对照组,两组比较差异有显著性(P<0.05)。结论氨氯地平片、氢氯噻嗪片、阿托伐他汀钙治疗舒张压升高的高血压病(2级高危组)是有效安全的方法。
Objective To observe the therapeutic efficacy of amlodipine tablets combined with atorvastatin calcium and hydroehlorothiazide tablets in the treatment of hypertension characterized by diastolic blood pressure increase. Methods Patients with hypertension （grade 2 high-risk group） were randomly divided into observation group （n = 30） and control group （n = 25）. The observation group received therapy using amlodipine tablets （5 mg q.d. ） combined with atorvastatin calcium （20 mg q.d. ） and hydrochlorothiazide tablets （25 mg q.d. ）, while the control group was given amlodipine tablets （5 mg q.d.） and hydrochlorothiazide tablets （25 mg q.d.）. The efficacies and adverse effects were observed within 8 weeks. Results In the observation group, 30 cases （100%） showed response, while in the control group, 21 cases （84%） showed response. The response rate was significantly higher in the observation group than in the control group （P〈0.05）. Conclusion Amlodipine tablets combined with atorvastatin calcium and hydrochlorothiazide tablets were effective and safe in the treatment of hypertension characterized by diastolic blood pressure increase （grade 2 high-risk group）.
出处
《心血管病防治知识（学术版）》
2012年第5期16-18,共3页
Prevention and Treatment of Cardiovascular Disease
关键词
氨氯地平
阿托伐他汀钙
氢氯噻嗪片
舒张压
Amlodipine
Atorvastatin calcium
Hydrochlorothiazide tablet
Diastolic pressure
