期刊文献+

地奈德乳膏与他克莫司软膏序贯疗法治疗面部复发性皮炎疗效观察 被引量:1

暂未订购
导出
摘要 目的观察外用0.05%地奈德乳膏与0.1%他克莫司软膏序贯疗法治疗30例面部复发性皮炎临床疗效和安全性。方法符合入选条件的60例面部复发性皮炎患者随机分为2组,各30例。实验组:先予外用0.05%地奈德乳膏早1次,0.1%他克莫司软膏晚1次,5d后改为每日早晚各擦1次0.1%他克莫司软膏,共10d。对照组:每日外用0.1%他克莫司软膏早晚各1次,连用10天。于治疗前及治疗后5d、10d观察临床疗效。结果试验组疗效明显优于对照组,不良反应少。结论应用0.05%地奈德乳膏与0.1%他克莫司软膏序贯疗法治疗面部复发性皮炎,安全、迅速、有效。
作者 邓淑萍
出处 《中国卫生产业》 2012年第21期48-48,共1页 China Health Industry
  • 相关文献

参考文献2

二级参考文献17

  • 1林宗贤 项蕾红.皮肤屏障功能研究进展[J].国际皮肤性病学杂志,2008,34(6):371-371.
  • 2Kao JS, Fluhr JW, Man MQ, et al. Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities. J Invest Dermatol, 2003, 120(3): 456-464.
  • 3Schoepe S, Schacke H, May E, et al. Glucocorticoid therapy- induced skin atrophy. Exp Dermatol, 2006, 15 (6): 406-420.
  • 4Kolbe L, Kligman AM, Schreiner V, et al. Corticosteroid-induced atrophy and barrier impairment measured by non-invasive methods in human skin. Skin Res Technol, 2001, 7 (2): 73-77.
  • 5Sheu HM, Lee JY, Chai CY, et al. Depletion of stratum intercellular lipid lamellae and barrier function abnormalities after long-term topical corticosteroids. Br J Dermatol, 1997, 136(6): 884-890.
  • 6van der Velden HM, Pasch MC, van Erp PE, et al. Treatment of plaque psoriasis with the two-compound product calcipotriol/ betamethasone dipropionate versus both monotherapies: an immunohistochemical study. J Dermatolog Treat, 2010, 21 (1): 13-22.
  • 7Jho SH, Radoja N, Im MJ, et al. Negative response elements in keratin genes mediate transcriptional repression and the crosstalk among nuclear receptors. J Biol Chem, 2001, 276 (49): 45914-45920.
  • 8Donet E, Bosch P, Sanchis A, et al. Transrepression function of the glucocorticoid receptor regulates eyelid development and keratinocyte proliferation but is not sufficient to prevent skin chronic inflammation. Mol Endocrinol, 2008, 22(4): 799-812.
  • 9Demerjian M, Choi EH, Man MQ, et al. Activators of PPARs and LXR decrease the adverse effects of exogenous glucocorticoids on the epidermis. Exp Dermatol, 2009, 18(7): 643-649.
  • 10Sandjeu Y, Haftek M. Desmosealin and other components of the epidermal extracellular matrix. J Physiol Pharmacol, 2009, Suppl 4: 23-30.

共引文献141

同被引文献4

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部