摘要
目的探讨盐酸纳美芬用于急性酒精中毒的临床疗效和安全性。方法将我院2010年11月～2011年11月收治的42例急性酒精中毒患者随机分为治疗组和对照组,每组21例。对照组给予常规治疗,治疗组在此基础上给予盐酸纳美芬治疗。观察患者清醒时间和不良反应发生情况。结果治疗组用药30min后病情好转、稳定。与对照组相比,治疗组的症状缓解时间明显优于对照组(P<0.05)。结论在常规治疗的基础上联合应用盐酸纳美芬抢救急性乙醇中毒,疗效稳定可靠,值得推广。
Objective To explore the therapeutic effects and safety of Nalmefene in treating acute alcoholic intoxication patients . Methods 42 patients with acute alcoholic intoxion from November 2010 to November 2011 were randomly divided into treatment group（21 cases）with Nalmefene and control greup（21 cases）. The patients in the control group were received routine treatment,while patients in the treatment group were treated with Nalmefene. The recovery time and side effect after treatment were observed. Results The patient＇s condition in treatment group was improving and stable after 30rain. The patients in the treatment group recoveryed quickly than the control group （P 〈 0. 05 ）. Conclusion Nalmefene is safe and effective for acute alcoholic in- toxication patients, thus its clinical use is worthy of recommendation.
出处
《四川医学》
CAS
2012年第8期1440-1441,共2页
Sichuan Medical Journal
关键词
纳美芬
急性酒精中毒
疗效观察
Nalmefene
acute alcoholic intoxication
therapeutic effects
