摘要
原发性甲状腺功能减退症（甲减）患者血中甲状腺激素水平降低，由于负反馈作用减弱使垂体增大，单纯影像学检查易与垂体瘤混淆；同时甲减合并肌酸激酶显著升高的病例也不少见，可能会被误诊为肌炎。本文介绍1例原发性甲减合并明显垂体增生、肌酸激酶升高患者的诊治过程，以引起对甲减非特异临床表现的重视，进行正确的治疗。
Pituitary hyperplasia may be found in patients with primary hypothyroidism as the decreased thyroid hormone level attenuates negative feedback effect. Sometimes the enlarged pituitary may be misdiagnosed as a pituitary tumor. Patients with long term untreated hypothyroidism often have extremely high level of serum creatine kinase and thus may be misdiagnosed as suffering from myositis. In order to increase the awareness of the nonspecific symptoms of primary hypothyroidism, this article introduces the diagnosis and treatment of a patient with primary hypothvroidism with raised serum creatine kinase level and pituitary hyperplasia.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2012年第9期761-764,共4页
Chinese Journal of Endocrinology and Metabolism
关键词
原发性甲状腺功能减退症
垂体增生
肌酸激酶
超微病理
Primary hypothyroidism Pituitary hyperplasia Creatine kinase Uhrastructural pathology
