摘要
回顾性分析2型糖尿病患者尿蛋白进展与凝血功能的关系。发现随着微量白蛋白尿的逐级增加，纤维蛋门原（FIB）明显增加，FIB是微量白蛋白尿升高的独立危险因素。且早期肾病进展至临床肾病组的基线FIB较非进展组升高[（3．5±0．9对3．0±0．6）g／L，P〈O．05]。FIB或可作为2型糖尿病尿蛋白进展的预测指标。
The association of coagulation function with progressive proteinuria in type 2 diabetic patients wasretrospectively analyzed. With increasing microalbuminuria, fibrinogen level was increased significantly. Fibrinogen was an independent risk factor of microalbuminuria. In patients as the early-stage diabetic nephropathy （ DN ） progressed to clinical-stage DN, the baseline level of fibrinogen was also increased [ （ 3.5 ±0.9 vs 3.0±0. 6 ） g/L, P〈0.05 ]. Fibrinogen may serve as a useful predictor of progressive proteinuria in type 2 diabetes.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2012年第9期726-728,共3页
Chinese Journal of Endocrinology and Metabolism
基金
围家自然科学基金项目（81072922,81173428）
关键词
糖尿病
2型
糖尿病肾病
凝血
蛋白尿
纤维蛋白原
Diabetes mellitus type 2 Diabetic nephropathies Coagulation Proteinuria Fibrinogen
