摘要
目的:观察薄芝糖肽联合利巴韦林治疗小儿手足口病的疗效及安全性。方法:将小儿手足口病普通型186例随机分为治疗组106例和对照组80例,两组均采用相同的基础治疗。治疗组用薄芝糖肽2 mL/次加入5%葡萄糖50～100 mL静脉滴注,1次/d,同时给予利巴韦林10 mg/kg加入5%葡萄糖100～150 mL中静脉滴注,1次/d。对照组仅给予利巴韦林治疗,剂量同上。结果:治疗组退热时间、口腔疼痛消失时间、皮疹消失时间、平均住院天数、并发症发生率均少于对照组,两组比较差异有统计学意义(P<0.01)。结论:薄芝糖肽联合利巴韦林治疗小儿手足口病疗效确切,不良反应少。
Understanding pediatric outpatient intravenous antimicrobial drug usage,in order to provide a basis for clinical rational use of antimicrobial agents.Methods： To study the intravenous drug use of pediatric outpatient infusion room in Hebei Provincial People’s Hospital from March 2011 to May 2011,to statistically analyze the use of antimicrobial agents,and to evaluate the rational use of drugs.Results： The rate of antibiotics use was 99.0% of intravenous drugs in pediatric outpatient,fifteen varieties of the a total of four categories.Cephalosporins,single-β-lactams and macrolides accounted for 32.1%,29.4% and 21.5%,respectively.Combined use of antimicrobial drugs accounted for 13.0% of total cases.All intravenous antibiotics were administrated once a day.Conclusions： Intravenous uses of antibiotics in pediatric patients were used generally.But there were some unreasonable phenomenon in antibacterial drug varieties selections,dosing frequency and combined medications.It should be paid more attention by the clinic.
出处
《儿科药学杂志》
CAS
2012年第9期25-27,共3页
Journal of Pediatric Pharmacy
关键词
薄芝糖肽
小儿
手足口病
Ganodermacapense glycopeptide
Children
Hand-foot-and-mouth disease
