摘要
目的探讨不同抗精神病药物对精神分裂症患者血糖、血脂的影响。方法选择首患精神分裂症患者286人,单一用不同抗精神病药物治疗。于治疗前及治疗8周后测定血糖、血脂。结果用抗精神药物患者8周后血糖值比未用抗精神药物患者血糖值增加非常显著(P<0.01);除氯氮平外其他药物治疗8周前后血脂值无显著变化(P>0.05)。结论多数抗精神病药物均有增加患者血糖的风险,氯氮平短期有增加血糖及血脂的风险,选择抗精神病药物要慎重。
Objective To compare the different antipsychotic drugs to patients with schizophrenia, blood sugar, blood fat influence. Method Choose a fine crack first in patients 286 people, a single use different antipsychotic treatment. In the treatment before and after treatment were eight weeks blood sugar, blood fat. Results With antidepressant drugs patients after eight weeks compared with glucose levels not antidepressant drugs patients blood sugar value increases very apparent （P〈0.01）, In addition to the clozapine other drug treatment aiter eight weeks ago blood fat no change.（P〉0.05）. Conclusion Most antipsychotic all have increased the risk of blood sugar levels in patients, with clozapine short term increase blood sugar and blood fat, choose the risk of antipsychotic drug carefully.
出处
《中国医药指南》
2012年第24期402-403,共2页
Guide of China Medicine
