摘要
目的观察评价注射用头孢哌酮钠舒巴坦钠治疗妇科感染的临床疗效及不良反应。方法选取妇科感染患者413例,分为试验组(206例)和对照组(207例)。试验组静脉滴注注射用头孢哌酮钠舒巴坦钠每次(中度)1.5 g或(重度)3.0 g、每8 h给药1次。对照组静脉滴注注射用头孢他啶,每次1.0 g(中度)或2.0 g(重度)、每8 h给药1次。结果试验组的临床痊愈率为50.97%,高于对照组的42.03%(P<0.05);两组总有效率分别为90.78%和81.64%,细菌清除率分别为89.19%和77.53%,差异具有统计学意义(P<0.05)。两组均未发现严重不良反应。结论注射用头孢哌酮钠舒巴坦钠治疗妇科感染的效果优于单用头孢他啶治疗,且未见明显不良反应。
Objective To investigate the clinical efficacy and adverse reactions of cefoperazone sodium and sulbactam sodium in the treatment of gynecological infections. Methods Four hundred and thirteen cases of gynecological infections were selected and divided into the test group and the control group. The test group was treated by cefoperazone sodium and sulbactam sodium for injection 1.5 g each time, once per 8 h （moderate） or 3.0 g once per 8 h （severe）. Results The curative rate was 50. 97% in the test group, which was higher than 42.03% in the control group with statistical difference between 2 groups（P〈 0.05）.The total effective rate was 90. 78% and 81.64%, and the bacterial clearance rate was 89. 19% and 77.53%, respectively, differences between 2 groups showing statistical significance （ P 〈 0.05 ）. No serious adverse reactions occurred in 2 groups. Conclusion The injection of cefoperazone sodium and sulbactam sodium is better than ceftazidime alone in the treatment of gynecological infections without obvious adverse reactions.
出处
《中国药业》
CAS
2012年第17期85-86,共2页
China Pharmaceuticals
关键词
头孢哌酮钠
舒巴坦钠
头孢他啶
妇科
细菌感染
对照观察
cefoperazone sodium
sulbactam sodium
ceftazidime
gynecology
bacterial infections
control observation
