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幼年强直性脊柱炎临床观察 被引量:1

Clinical observation of juvenile ankylosing spondylitis
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摘要 目的探讨幼年强制性脊柱炎的治疗方法及疗效。方法将广西梧州市桂东人民医院2007年1月至2011年8月收治的100例幼年强直性脊柱炎患儿分为治疗组和对照组,治疗组采用雷公藤片治疗,对照组采用西药常规治疗(奈普生或布洛芬、小剂量泼尼松),比较两组治疗效果。结果两组患儿在晨僵时间、关节疼痛指数、关节肿胀指数、关节功能障碍指数、血沉、血色素、C反应蛋白方面均无显著性差异(P>0.05)。但治疗组的毒副作用显著少于对照组(P<0.05)。结论公藤片与西药常规治疗幼年强直性脊柱炎疗效相当,但雷公藤片的毒副作用较少,适合幼儿治疗。 Objective To investigate the treatment method and curative effect of the juvenile ankylosing spondylitis. Methods Totally 100 eases of juvenile ankylosing spondylitis patients in our hospital from 2007 January to 2011 August were divided into the treatment group and the control group, the treatment group was given Tripterygium glycoside, the control group was given conventional treatment of Western Medicine (naproxen or ibuprofen, small doses of prednisone), the effect of the two groups were compared. Results The duration of morning stiffness, joint pain index, swelling index, index, erythrocyte sedimentation rate, hemoglobin joint dysfunction, C reactive protein were no significant difference between the two groups ( P 〉 0. 05 ). The toxicity and side effects in the treatment group were significantly less than that in the control group ( P 〈 0. 05 ). Condusions Tripterygium glycoside and routine western medicine treatment were in equivalent efficacy for juvenile ankylosing spondylitis, but the toxicity of Tripterygium glycoside has less side effects, and suitable for children treatment.
作者 李东良
出处 《医药论坛杂志》 2012年第9期40-41,共2页 Journal of Medical Forum
关键词 幼年 强直性脊柱炎 雷公藤片 治疗 疗效 Juvenile Ankylosing spondylitis Tripterygium glycoside Treatment Curative effect
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  • 1李瑞林 舒达夫.雷公藤的研究与临床应用[M].北京:中国科学技术出版社,1989.360-361.
  • 2中华医学会.临床技术操作规范风湿病分册[M].北京:人民卫生出版社,2005.23-24.
  • 3周纬,殷蕾,杨珍.幼年特发性关节炎28例诊断治疗分析[J].中国实用儿科杂志,2003,18(2):99-100. 被引量:10

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