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补阳还五汤对急性脑梗塞下丘脑—垂体—甲状腺轴内分泌激素变化的影响及临床观察 被引量:5

Clinical Studies on Buyang Huanwu Decoction on the Hormone Changes in Hypothalamus-Pituitary-Thyroid Axis in Patients with Cerebral Infarction
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摘要 目的 :探讨补阳还五汤对急性脑梗塞的临床疗效及对患者下丘脑—垂体—甲状腺轴内分泌激素变化的影响。方法 :68例患者随机分为治疗组与对照组 ,每组 34例 ,治疗组用补阳还五汤加低分子右旋糖酐治疗 ;对照组用低分子右旋糖酐和肠溶阿司匹林治疗 ,观察治疗前后三碘甲状腺原氨酸 ( T3)、甲状腺素 ( T4 )、游离三碘甲状腺原氨酸 ( FT3)、游离甲状腺素 ( FT4 )、促甲状腺素( TSH)水平的变化与临床疗效。结果 :治疗组疗效优于对照组 ( P<0 .0 5)。治疗后治疗组的 T3、FT3和 TSH由治疗前的低水平升高至正常范围 ,两组用药后各指标变化比较 ,在 T3、FT3、TSH有明显变化 ( P<0 .0 1)。结论 :本研究表明了补阳还五汤在低分子右旋糖酐改善微循环作用的基础上发挥了更有效的治疗作用 。 Objective:To assess the effects of Buyang Huanwu Decoction (BHD) in treating cerebral infarction and the hormone changes in HypothalamusPituitaryThyroid Axis.Methods:68 cases cerebral infarction patients were divided at random into two groups:BHD group (34 cases treated with dextran and BHD taken orally) and control group (35 cases treated with dextran and aspirin tablets). Detections were made on triiodothyronine (T3),thyroxine (T4),free triiodothyronine (FT3),free thyroxine (FT4) and thyroid stimulating hormone (TSH) before and after the treatment.Results:Compared with the control group,the hormone levels of T 3,FT 3 and TSH in BHD group were significantly raised after the treatment (P<0.01). Conclusions:BHD had the curative effects for the cerebral infarction under the improved microcirculation induced by dextran and as well as the regulating effects on the hypothalamuspituitarythyroid axis disorder.
作者 黄婷 李恩宽
出处 《浙江中西医结合杂志》 2000年第5期257-259,共3页 Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
关键词 补阳还五汤 急性 脑梗塞 激素分泌 治疗 Buyang Huanwu decoction acute cerebral infarction hypothalamus-pituitary-thyroid axis hormone secretion
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  • 1路超,中华内分泌代谢杂志,1988年,4卷,29页
  • 2缪珩,中华内分泌代谢杂志,1988年,4卷,182页
  • 3孟家眉,中华神经精神科杂志,1988年,21卷,57页
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