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血管瘤患者尿液中血管内皮细胞生因子水平变化及其意义的研究

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摘要 目的探讨血管瘤患者尿液中血管内皮细胞生因子水平变化和临床意义。方法用免疫酶标技术分别检21例增生期血管瘤,12例消退期血管瘤及8例对照组婴儿尿液中血管内皮细胞生因子(VEGF)的浓度。结果 21例增生期血管瘤患儿尿液中VEGF平均含量(553.17±79.80)ng/mL,12例消退期血管瘤为(294.00±65.70)ng/mL,两者差别有显著性意义(P<0.05)。8例对照组为(229.90±55.72)ng/mL,与实验组有显著性差异;消退期血管瘤与对照组尿液中VEGF浓度,无显著性差异。结论酶联免疫吸附技术可以简便、无创的检测不同时期血管瘤患儿尿液中的VEGF浓度;VEGF浓度的测定可以为血管瘤的治疗方案的选择提供依据。
出处 《中国医药指南》 2012年第23期122-123,共2页 Guide of China Medicine
基金 广东省医学科研基金项目 编号:A2008444
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