摘要
目的研究左心室三维应力与反映左心室收缩功能的生物力学指标——最大心肌劲度(maxEav)的相关性,以获得反映左心室收缩功能的简单且实用的生物力学指标。方法选取34例健康人为研究对象,其中男性19例,女性15例;年龄34～75岁,平均年龄49.2岁。应用超声心动图测定心脏左心室收缩末期内径和后壁厚度及射血分数;左心室收缩末期中壁长短径、室壁厚度;联合袖带肱动脉血压值计算左心室收缩末期压力。应用上述各测值计算maxEav及左心室收缩末期径线、圆周、长轴应力(σr、σθ、σm),进行相关性统计学分析。结果σr=(-62.55±0.53)N/cm2;σθ=(27.81±1.36)N/cm2;σm=(62.58±2.88)N/cm2;maxEav=(226.52±9.36)N/cm2;LVEF=(63.13±1.01)%。maxEav与σr无相关性(r=0.067,P>0.05);maxEav与σθ有极显著负相关性(r=-0.510,P<0.01);maxEav与σm有极显著正相关性(r=0.563,P<0.01)。LVEF与三向应力无相关性(P>0.05)。结论应用左心室收缩末期圆周及长轴应力两项生物力学指标评价左心室收缩功能较为简便实用且准确。
Objective To study the correlation of three-dimensional stress and maximum myocardial stiffness （maxEav）, and obtain the useful mechanical index for reflecting left ventricular systolic function. Methods A total of 34 healthy people were enrolled, male 19, female 15, aged 34 - 75 years old, mean age 49.2 years old. The left ventricular end-systolic dimension （LVEDs）, posterior wall thickness（LVPWs）, mid-wall long axis diameter（Lines）, mid- wall short axis diameter （Dines） and wall thiekness（Hes）, left ventricular ejection fraction（LVEF） were determined by eehoeardiography. The brachial blood pressure was recorded to calculate the left ventrieular end-systolic pressure（Pes）. The values got from eehoeardiography were used to calculate the maxEav, the left ventricular radial stress （σr）, end-systolic circumferential stress （θr） and meridional stress（σm）. The statistic analysis of correlation in maxEav and three-dimensional stress, and between EF and three-dimensional stress were analyzed. Results The results as follows： σr = （- 62.55 ± 0.53） N/cm2; σθ = （27.81 ± 1.36） N/cm2; cm^2 = （62.58 ± 2.88） N/cm2; maxEav = （226.52 ± 9.36） N/cm2; LVEF = （63.13 ± 1.01） %. The maxEav had no correlation with σr （r=0.067, P〉 0.05）, and maxEav had the negative correlation with σθ（r = - 0.510, P 〈 0.01）. The maxEav had correlation with σθ（r = 0.563, P 〈 0.01）, and LVEF had no correlation with three-dimensional stress（P 〉 0.05）. Conclusion It is demonstrated that the left ventrieular circumferential stress
出处
《生物医学工程与临床》
CAS
2012年第5期446-449,共4页
Biomedical Engineering and Clinical Medicine
关键词
左心室三维应力
最大心肌劲度
左心室收缩功能
left ventricular three-dimensional stress
maximum myocardial stiffness（maxEav）
left ventricular systolic function
