摘要
本文收集1984年9月至1988年6月在我院手术的AFP阴性肝癌及非肝癌肝占位性病变59例。术前用4～30％聚丙烯酰胺梯度凝胶电泳法测定其血清r—谷氨酰转肽酶同工酶。此同工酶的Ⅰ＇、Ⅱ、Ⅱ＇带为原发性肝癌特异性区带。AFP阴性肝癌出现特异性区带者占66.7％(22/33),转移性肝癌占10％(1/10)肝血管瘤等不出现特异性区带。结果表明r—谷氨酰转肽酶同工酶对AFP阴性肝癌的诊断有较大意义。
The Serum y—glutamyl transpeptidase isoenzyme (y—GT isoenzyme) were assayed in 59 patients with Primary liver cancer or other Space-occupying lesions. The serum AFP concentration of all patients were less than 400ng/ml. Using 4～30％ Polyacrylamide gradient gel electrophoresis, it was found that bandⅠ′、 Ⅱ、Ⅱ′of y—GT isoenzyme were specific for primary liver cancer (PLC) . One or more specific bands were presented in 66.7％ of the patients with PLC, in82.5％ of the Patients with small PLCo No Specific bands were presented in patients with benign liver lesion, we concluded that y—GT isoensyme may be a specific tumor markern of PLC.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1990年第1期16-18,共3页
Cancer Research on Prevention and Treatment
