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联合用药治疗原发性肝癌82例近期疗效分析

MULTIMODALITY OF CHEMOTHERAPY FOR 82 PATIENTS WITH PRIMARY LIVER CANCER
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摘要 多数原发性肝癌(简称PHC)确诊后已属中晚期,适合手术或放射治疗者较少。国外报道1975年以前手术切除率为5.7~7%,我国1971~1982年为30.0%。多数病人需化学药物治疗。我科1977年3月~1988年5月采取多个联合化疗方案治疗82例PHC,近期疗效如下。 From March 1977 to May 1988, 82 primary liver cancer patients were treated withseven anticancer drugs in various combinations:(1) MOF for 36 cases, with a reponserate of 19.4%; (2) MAF, 17 cases, 29.4%; (3) MOAn, 6 cases, 33.3%; (4) MOU, 13cases, 53.8%; and (5) MPU, 10 cases, 40%. The dosage used for each patient wasmoderate or small, and supplemented with traditional drugs, so that most of the patientscould take one therapeutic course without complain. Only 10 cases suffered severegastrointestinal toxicity (nausea, vomiting); WBC dropped below 4000 in 12 cases. Theresult indicated that MOU and MPU gave a better therapeutic effect. A: AT1258, nitrocaphanum; An: Emulsio Fluorouracil Compositae; F: 5-Fluoro-uracil; M: Mitomycin C; O: Oncovin, Vincristinum; P. Cis Platinum Diaminedichloride; U: FT207, Tegafuri compositae.
出处 《肿瘤》 CAS CSCD 北大核心 1990年第3期119-120,共2页 Tumor
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